PACS2 Products
(phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))
Categories
Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
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Featured PACS2 Categories
PACS2 Antibodies
High quality antibodies with extensive validation data.
PACS2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PACS2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7163270
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN657066
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7163273
Quantity
100 μg
Datasheet
Datasheet
Recommended PACS2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6233897
Quantity
96 tests
Datasheet
Datasheet
Recommended PACS2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313862
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422313
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094328
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PACS2 products
: "Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis." in: Molecular cell, Vol. 34, Issue 4, pp. 497-509, (2009) (PubMed).Synonyms and alternative names related to PACS2
phosphofurin acidic cluster sorting protein 2 (PACS2), phosphofurin acidic cluster sorting protein 2 (Pacs2), 6720425G15Rik, AW208651, AW489976, E230011J22, mKIAA0602, PACS-2, PACS1L, Pacs1lProtein level used designations for PACS2
- PACS1-like protein
- PACS-2
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