OTU Domain, Ubiquitin Aldehyde Binding 1 Products
(OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].
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Featured OTU Domain, Ubiquitin Aldehyde Binding 1 Categories
OTU Domain, Ubiquitin Aldehyde Binding 1 Antibodies
High quality antibodies with extensive validation data.
OTU Domain, Ubiquitin Aldehyde Binding 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended OTU Domain, Ubiquitin Aldehyde Binding 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p), FACS
Validations
- (12)
Cat. No.
ABIN1499930
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IHC (p)
Validations
- (11)
Cat. No.
ABIN1499932
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (10)
Cat. No.
ABIN1499933
Quantity
100 μL
Datasheet
Datasheet
Recommended OTU Domain, Ubiquitin Aldehyde Binding 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313747
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7197259
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2130969
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our OTU Domain, Ubiquitin Aldehyde Binding 1 products
: "OTUB1 inhibits CNS autoimmunity by preventing IFN-γ-induced hyperactivation of astrocytes." in: The EMBO journal, Vol. 38, Issue 10, (2019) (PubMed).: "Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion." in: The FEBS journal, Vol. 277, Issue 11, pp. 2515-30, (2010) (PubMed).
: "Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry." in: FEBS letters, Vol. 580, Issue 1, pp. 179-83, (2006) (PubMed).
Synonyms and alternative names related to OTU Domain, Ubiquitin Aldehyde Binding 1
OTU deubiquitinase, ubiquitin aldehyde binding 1 (OTUB1), OTU domain, ubiquitin aldehyde binding 1 (Otub1), OTU deubiquitinase, ubiquitin aldehyde binding 1 (Otub1), OTU deubiquitinase, ubiquitin aldehyde binding 1b (otub1b), OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog (otub1.L), OTU domain, ubiquitin aldehyde binding 1 (otub1), OTU domain, ubiquitin aldehyde binding 1 (OTUB1), similar to HSPC263 (RGD1565010), OTU deubiquitinase, ubiquitin aldehyde binding 1a (otub1a), AI850305, fa19h07, fb17f04, MGC131231, OTB1, OTU1, otub1, otub1l, wu:fa19h07, wu:fb17f04, zgc:92685, zgc:92839Protein level used designations for OTU Domain, Ubiquitin Aldehyde Binding 1
- OTU domain-containing ubiquitin aldehyde-binding protein 1
- OTU-domain Ubal-binding 1
- deubiquitinating enzyme OTUB1
- otubain-1
- ubiquitin thioesterase OTUB1
- ubiquitin-specific protease otubain 1
- ubiquitin-specific-processing protease OTUB1
- otubain 1
- OTU domain, ubiquitin aldehyde binding 1
- Ubiquitin thioesterase OTUB1
- ubiquitin thioesterase otub1
- OTU deubiquitinase, ubiquitin aldehyde binding 1a
- OTU domain, ubiquitin aldehyde binding 1, like
- OTU domain, ubiquitin aldehyde binding 1a
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