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OTU Domain Containing 5 Products

(OTU Domain Containing 5 (OTUD5))

Categories

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008].

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Featured OTU Domain Containing 5 Categories

OTU Domain Containing 5 Antibodies

High quality antibodies with extensive validation data.

OTU Domain Containing 5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended OTU Domain Containing 5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7162334
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN960300
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN2690260
Quantity 100 μL
Datasheet Datasheet

Recommended OTU Domain Containing 5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969102
Quantity 96 tests
Datasheet Datasheet

Recommended OTU Domain Containing 5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313754
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3085156
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3121939
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our OTU Domain Containing 5 products

Kayagaki, Phung, Chan, Chaudhari, Quan, ORourke, Eby, Pietras, Cheng, Bazan, Zhang, Arnott, Dixit: "DUBA: a deubiquitinase that regulates type I interferon production." in: Science (New York, N.Y.), Vol. 318, Issue 5856, pp. 1628-32, (2007) (PubMed).

Synonyms and alternative names related to OTU Domain Containing 5

OTU deubiquitinase 5 (OTUD5), OTU domain containing 5 (Otud5), OTU deubiquitinase 5 (Otud5), OTU deubiquitinase 5a (otud5a), OTU deubiquitinase 5 S homeolog (otud5.S), OTU deubiquitinase 5 L homeolog (otud5.L), OTU deubiquitinase 5b (otud5b), AA407879, AI553596, BB114028, DUBA, DXImx46e, otud5, Sfc7, si:bz30i22.1, si:rp71-30i22.1, wu:fi28a06, zgc:100839, zgc:154072

Protein level used designations for OTU Domain Containing 5

  • OTU domain-containing protein 5
  • deubiquinating enzyme A
  • deubiquitinating enzyme A
  • DUBA
  • OTU domain containing 5
  • OTU domain-containing protein 5-A
  • LOW QUALITY PROTEIN: OTU domain-containing protein 5
  • OTU deubiquitinase 5b
  • OTU domain containing 5b
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