OTC Products
(Ornithine Carbamoyltransferase (OTC))
Categories
This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008].
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Featured OTC Categories
OTC Antibodies
High quality antibodies with extensive validation data.
OTC ELISA Kits
Reliable ELISA kits for a wide range of species.
OTC Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended OTC Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7433690
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN6145081
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB, IHC
Validations
- (4)
- (4)
Cat. No.
ABIN2773791
Quantity
100 μL
Datasheet
Datasheet
Recommended OTC ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969077
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962951
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958320
Quantity
96 tests
Datasheet
Datasheet
Recommended OTC Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124272
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124271
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313731
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our OTC products
: "A new mouse model of mild ornithine transcarbamylase deficiency (spf-j) displays cerebral amino acid perturbations at baseline and upon systemic immune activation." in: PLoS ONE, Vol. 10, Issue 2, pp. e0116594, (2015) (PubMed).: "Acute metabolic decompensation due to influenza in a mouse model of ornithine transcarbamylase deficiency." in: Disease models & mechanisms, Vol. 7, Issue 2, pp. 205-13, (2014) (PubMed).
: "GLTSCR2/PICT1 links mitochondrial stress and Myc signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 10, pp. 3781-6, (2014) (PubMed).
: "Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction." in: Molecular cell, Vol. 41, Issue 2, pp. 139-49, (2011) (PubMed).
: "Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 6, pp. 1100-17, (2010) (PubMed).
: "Urea cycle gene expression is suppressed by PFOA treatment in rats." in: Toxicology letters, Vol. 197, Issue 1, pp. 46-50, (2010) (PubMed).
: "Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13669-75, (2009) (PubMed).
: "A quantitative proteomic approach for identification of potential biomarkers in hepatocellular carcinoma." in: Journal of proteome research, Vol. 7, Issue 10, pp. 4289-98, (2008) (PubMed).
: "Proteomics in free-living Mus spretus to monitor terrestrial ecosystems." in: Proteomics, Vol. 7, Issue 23, pp. 4376-87, (2007) (PubMed).
: "Hyperammonemia-induced encephalopathy due to ornithine transcarbamylase deficiency in an adult woman: identification of novel missense mutations." in: Journal of gastroenterology, Vol. 40, Issue 1, pp. 106-7, (2005) (PubMed).
Synonyms and alternative names related to OTC
ornithine carbamoyltransferase (OTC), plexin A2 (Plxna2), ornithine carbamoyltransferase (Otc), ornithine carbamoyltransferase (argF), ornithine carbamoyltransferase ArgF (argF), ornithine carbamoyltransferase (argF-2), ornithine carbamoyltransferase (atpD-2), ornithine carbamoyltransferase (CNC04300), plexin A2 (PLXNA2), ornithine transcarbamylase (Otc), ornithine carbamoyltransferase (otc), 2810428A13Rik, AA589422, AI265390, AW457381, BA4351, F1B16.13, F1B16_13, mKIAA0463, OCT, OCTD, ORNITHINE CARBAMOYLTRANSFERASE, ornithine carbamoyltransferase, Plxn2, PLXN2, PSPTO4164, Sf, si:dkey-19h21.3, spfProtein level used designations for OTC
- OTCase
- ornithine carbamoyltransferase, mitochondrial
- ornithine transcarbamylase
- plex 2
- plexin 2
- plexin-2
- plexin-A2
- ornithine carbamoyltransferase
- semaphorin receptor OCT
- transmembrane protein OCT
- sparse fur
- LOW QUALITY PROTEIN: ornithine carbamoyltransferase, mitochondrial
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