Osteoprotegerin Products
(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
Categories
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].
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Featured Osteoprotegerin Categories
Osteoprotegerin Antibodies
High quality antibodies with extensive validation data.
Osteoprotegerin ELISA Kits
Reliable ELISA kits for a wide range of species.
Osteoprotegerin Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Osteoprotegerin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (7)
Cat. No.
ABIN3022915
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7431044
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7431047
Quantity
100 μL
Datasheet
Datasheet
Recommended Osteoprotegerin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (17)
- (1)
Cat. No.
ABIN6960288
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6960286
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (9)
- (1)
Cat. No.
ABIN6960285
Quantity
96 tests
Datasheet
Datasheet
Recommended Osteoprotegerin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275758
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275769
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293T Cells
Validations
- (2)
Cat. No.
ABIN1323154
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our Osteoprotegerin products
: "Bone Remodeling in Mandible of Wistar Rats with Diabetes Mellitus and Osteoporosis." in: European journal of dentistry, (2022) (PubMed).: "3D Environment Is Required In Vitro to Demonstrate Altered Bone Metabolism Characteristic for Type 2 Diabetics." in: International journal of molecular sciences, Vol. 22, Issue 6, (2021) (PubMed).
: "Development and characterization of supramolecular calcitonin assembly and assessment of its interactions with the bone remodelling process." in: Bone, Vol. 122, pp. 123-135, (2020) (PubMed).
: "IL-38 restrains inflammatory response of collagen-induced arthritis in rats via SIRT1/HIF-1α signaling pathway." in: Bioscience reports, Vol. 40, Issue 5, (2020) (PubMed).
: "QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism." in: Cell death & disease, Vol. 11, Issue 5, pp. 330, (2020) (PubMed).
: "The impact of forced swimming on expression of RANKL and OPG in a type 2 diabetes mellitus rat model." in: Archives of physiology and biochemistry, Vol. 125, Issue 3, pp. 195-200, (2019) (PubMed).
: "The Effects of Quassinoid-Rich Eurycoma longifolia Extract on Bone Turnover and Histomorphometry Indices in the Androgen-Deficient Osteoporosis Rat Model." in: Nutrients, Vol. 10, Issue 7, (2019) (PubMed).
: "Role of interleukin-33 in the clinical pathogenesis of chronic apical periodontitis." in: The Journal of international medical research, Vol. 47, Issue 7, pp. 3332-3343, (2019) (PubMed).
: "Alveolar Bone Density Reduction in Rats Caused by Unilateral Nasal Obstruction" in: Balkan medical journal, Vol. 36, Issue 6, pp. 311-319, (2019) (PubMed).
: "Comparing the Osteogenic Potentials and Bone Regeneration Capacities of Bone Marrow and Dental Pulp Mesenchymal Stem Cells in a Rabbit Calvarial Bone Defect Model." in: International journal of molecular sciences, Vol. 20, Issue 20, (2019) (PubMed).
Synonyms and alternative names related to Osteoprotegerin
TNF superfamily member 11 (TNFSF11), TNF receptor superfamily member 11b (TNFRSF11B), tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b), TNF receptor superfamily member 11B (Tnfrsf11b), tumor necrosis factor receptor superfamily member 11b S homeolog (tnfrsf11b.S), tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B), CD254, hRANKL2, OCIF, ocif, ODF, OPG, Opg, opg, OPGL, OPTB2, RANKL, sOdf, TR1, tr1, TRANCEProtein level used designations for Osteoprotegerin
- TNF-related activation-induced cytokine
- osteoclast differentiation factor
- osteoprotegerin ligand
- receptor activator of nuclear factor kappa B ligand
- receptor activator of nuclear factor kappa-B ligand
- tumor necrosis factor ligand superfamily member 11
- osteoclastogenesis inhibitory factor
- osteoprotegerin
- tumor necrosis factor receptor superfamily member 11B
- Osteoprotegerin
- tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
- tumor necrosis factor receptor superfamily, member 11b
- tumor necrosis factor receptor superfamily member 11B-like
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