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OSBP Products

(Oxysterol Binding Protein (OSBP))
Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [provided by RefSeq, Jul 2008].

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Featured OSBP Categories

OSBP Antibodies

High quality antibodies with extensive validation data.

OSBP ELISA Kits

Reliable ELISA kits for a wide range of species.

OSBP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended OSBP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6263909
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN1327081
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1681171
Quantity 100 μg
Datasheet Datasheet

Recommended OSBP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1146710
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1146711
Quantity 96 tests
Datasheet Datasheet

Recommended OSBP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313670
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419181
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2727973
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our OSBP products

Roberts, Severance, Bensen, Le, Kothapalli, Nuñez, Ma, Wu, Standke, Yang, Reddig, Blewett, Burgett: "Transient Compound Treatment Induces a Multigenerational Reduction of Oxysterol-Binding Protein (OSBP) Levels and Prophylactic Antiviral Activity." in: ACS chemical biology, Vol. 14, Issue 2, pp. 276-287, (2019) (PubMed).

Roberts, Severance, Bensen, Le-McClain, Malinky, Mettenbrink, Nuñez, Reddig, Blewett, Burgett: "Differing activities of oxysterol-binding protein (OSBP) targeting anti-viral compounds." in: Antiviral research, Vol. 170, pp. 104548, (2019) (PubMed).

Storey, McIntosh, Huang, Landrock, Martin, Landrock, Payne, Atshaves, Kier, Schroeder: "Intracellular cholesterol-binding proteins enhance HDL-mediated cholesterol uptake in cultured primary mouse hepatocytes." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 8, pp. G824-39, (2012) (PubMed).

Moorhead, Jung, Smirnov, Kaufer, Scidmore: "Multiple host proteins that function in phosphatidylinositol-4-phosphate metabolism are recruited to the chlamydial inclusion." in: Infection and immunity, Vol. 78, Issue 5, pp. 1990-2007, (2010) (PubMed).

Takeshita, Ishida, Akamatsu, Ohmori, Sudoh, Uto, Tsubouchi, Kataoka: "Proanthocyanidin from blueberry leaves suppresses expression of subgenomic hepatitis C virus RNA." in: The Journal of biological chemistry, Vol. 284, Issue 32, pp. 21165-76, (2009) (PubMed).

Amako, Sarkeshik, Hotta, Yates, Siddiqui: "Role of oxysterol binding protein in hepatitis C virus infection." in: Journal of virology, Vol. 83, Issue 18, pp. 9237-46, (2009) (PubMed).

Romeo, Kazlauskas: "Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1." in: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9595-605, (2008) (PubMed).

Wang, Weng, Anderson: "OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation." in: Science (New York, N.Y.), Vol. 307, Issue 5714, pp. 1472-6, (2005) (PubMed).

Moreira, Jaworski, Li, Rodriguez: "Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina." in: The Journal of biological chemistry, Vol. 276, Issue 21, pp. 18570-8, (2001) (PubMed).

Wilson, Guerrette, Fishel: "Dissociation of mismatch recognition and ATPase activity by hMSH2-hMSH3." in: The Journal of biological chemistry, Vol. 274, Issue 31, pp. 21659-64, (1999) (PubMed).

Synonyms and alternative names related to OSBP

Oxysterol binding protein (Osbp), oxysterol binding protein (OSBP), oxysterol binding protein (Osbp), 1110018F06Rik, AW559088, CG6708, Dmel\\CG6708, mKIAA4220, osbp, OSBP-Dm, OSBP1

Protein level used designations for OSBP

  • CG6708-PA
  • Osbp-PA
  • oxysterol binding protein
  • oxysterol-binding protein
  • oxysterol-binding protein 1
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