OPCML Products
(Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))
Categories
This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured OPCML Categories
OPCML Antibodies
High quality antibodies with extensive validation data.
OPCML Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended OPCML Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN6263790
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN1881594
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IHC
Validations
- (2)
Cat. No.
ABIN1804627
Quantity
50 μL
Datasheet
Datasheet
Recommended OPCML ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4884030
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386192
Quantity
96 tests
Datasheet
Datasheet
Recommended OPCML Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313406
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7320058
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7317147
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our OPCML products
: "Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions." in: Nature communications, Vol. 10, Issue 1, pp. 3134, (2019) (PubMed).: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
: "Comparison of gene expression profiles between primary tumor and metastatic lesions in gastric cancer patients using laser microdissection and cDNA microarray." in: World journal of gastroenterology, Vol. 12, Issue 43, pp. 6949-54, (2006) (PubMed).
: "OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer." in: Nature genetics, Vol. 34, Issue 3, pp. 337-43, (2003) (PubMed).
: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
Synonyms and alternative names related to OPCML
opioid binding protein/cell adhesion molecule like (OPCML), opioid binding protein/cell adhesion molecule-like (Opcml), 2900075O15Rik, 3732419F12, AI844366, B930023M13Rik, C230027C17, Gm181, IGLON1, OBCAM, Obcam, OPCMProtein level used designations for OPCML
- IgLON family member 1
- opioid binding protein/cell adhesion molecule-like preprotein
- opioid-binding protein/cell adhesion molecule
- opioid binding cell adhesion molecule
- OBCAM
- opioid-binding cell adhesion molecule
- opioid-binding protein/cell adhesion molecule-like
- OBCAM alpha 1 isoform
- OBCAM protein gamma isoform
- neurite inhibitor GP55-A
- opioid-binding protein/cell adhesion molecule homolog
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