OPA1 Products
(Optic Atrophy 1 (Autosomal Dominant) (OPA1))
Categories
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
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Featured OPA1 Categories
OPA1 Antibodies
High quality antibodies with extensive validation data.
OPA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended OPA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (6)
Cat. No.
ABIN6145031
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (6)
Cat. No.
ABIN2565745
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN3043457
Quantity
100 μg
Datasheet
Datasheet
Recommended OPA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN419938
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN427337
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN434335
Quantity
96 tests
Datasheet
Datasheet
Recommended OPA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313400
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313399
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7424116
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our OPA1 products
: "Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 3, pp. 4458-4472, (2019) (PubMed).: "Mitochondrial transplantation regulates antitumour activity, chemoresistance and mitochondrial dynamics in breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 30, (2019) (PubMed).
: "Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells." in: Nature, Vol. 558, Issue 7708, pp. 141-145, (2018) (PubMed).
: "Copper-Mediated Mitochondrial Fission/Fusion Is Associated with Intrinsic Apoptosis and Autophagy in the Testis Tissues of Chicken." in: Biological trace element research, (2018) (PubMed).
: "Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia." in: Scientific reports, Vol. 8, Issue 1, pp. 7233, (2018) (PubMed).
: "L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury." in: Scientific reports, Vol. 8, Issue 1, pp. 11201, (2018) (PubMed).
: "Maternal L-Carnitine Supplementation Improves Brain Health in Offspring from Cigarette Smoke Exposed Mothers." in: Frontiers in molecular neuroscience, Vol. 10, pp. 33, (2017) (PubMed).
: "Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." in: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).
: "Protective responses to sublytic complement in the retinal pigment epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 31, pp. 8789-94, (2016) (PubMed).
: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." in: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).
Synonyms and alternative names related to OPA1
OPA1, mitochondrial dynamin like GTPase (Opa1), OPA1, mitochondrial dynamin like GTPase (OPA1), optic atrophy 1 (autosomal dominant) (opa1), 1200011N24Rik, AI225888, AI847218, fk62d06, largeG, lilr3, MGM1, mKIAA0567, NPG, NTG, wu:fb77a10, wu:fk62d06, zgc:92092Protein level used designations for OPA1
- dynamin-like 120 kDa protein, mitochondrial
- large GTP-binding protein
- largeG
- optic atrophy 1 homolog
- optic atrophy protein 1 homolog
- RN protein
- optic atrophy 1 (autosomal dominant)
- optic atrophy 1-like protein
- dynamin-like guanosine triphosphatase
- mitochondrial dynamin-like GTPase
- optic atrophy protein 1
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