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Obscurin Products

(Obscurin (OBSCN))

Categories

The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured Obscurin Categories

Obscurin Antibodies

High quality antibodies with extensive validation data.

Obscurin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Obscurin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7162115
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7269076
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (1)
Cat. No. ABIN529547
Quantity 50 μL
Datasheet Datasheet

Recommended Obscurin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6233432
Quantity 96 tests
Datasheet Datasheet

Recommended Obscurin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313313
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313315
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Obscurin products

Shriver, Stroka, Vitolo, Martin, Huso, Konstantopoulos, Kontrogianni-Konstantopoulos: "Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis." in: Oncogene, Vol. 34, Issue 32, pp. 4248-59, (2015) (PubMed).

Hu, Kontrogianni-Konstantopoulos: "The kinase domains of obscurin interact with intercellular adhesion proteins." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 5, pp. 2001-12, (2013) (PubMed).

Synonyms and alternative names related to Obscurin

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN), obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Obscn), ARHGEF30, BC046431, Gm878, OTTMUSG00000005786, UNC89

Protein level used designations for Obscurin

  • obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  • obscurin
  • obscurin, myosin light chain kinase
  • obscurin-MLCK
  • obscurin-RhoGEF
  • obscurin-myosin light chain kinase
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