Obestatin Products
(Obestatin (OB))
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This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake\; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq, Oct 2008].
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Featured Obestatin Categories
Obestatin Antibodies
High quality antibodies with extensive validation data.
Obestatin ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended Obestatin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA
Validations
- (1)
Cat. No.
ABIN1169352
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC
Validations
Cat. No.
ABIN3180771
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB
Validations
Cat. No.
ABIN4902035
Quantity
100 μL
Datasheet
Datasheet
Recommended Obestatin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958291
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6975673
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6969040
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our Obestatin products
: "Acute effect of smoking and smoking abstinence on energy intake and appetite-related hormones blood concentrations." in: Physiology & behavior, Vol. 184, pp. 78-82, (2018) (PubMed).: "Ghrelin and obestatin plasma levels and ghrelin/obestatin prepropeptide gene polymorphisms in small for gestational age infants." in: The Journal of international medical research, Vol. 42, Issue 6, pp. 1232-42, (2015) (PubMed).
: "Is association between thyroid hormones and gut peptides, ghrelin and obestatin, able to suggest new regulatory relation between the HPT axis and gut?" in: Regulatory peptides, Vol. 189, pp. 17-21, (2014) (PubMed).
: "Plasma Ghrelin Concentrations Are Negatively Correlated With Urine Albumin-to-Creatinine Ratio in Newly Diagnosed Type 2 Diabetes." in: The American journal of the medical sciences, (2014) (PubMed).
: "Significance of appetite hormone ghrelin and obestatin levels in the assessment of the severity of acute pancreatitis." in: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, Vol. 25, Issue 3, pp. 309-13, (2014) (PubMed).
: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)
: "The ghrelin/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake." in: Journal of neuroendocrinology, Vol. 22, Issue 7, pp. 793-804, (2010) (PubMed).
: "Covariation of plasma ghrelin and motilin in irritable bowel syndrome." in: Peptides, Vol. 31, Issue 6, pp. 1109-12, (2010) (PubMed).
Synonyms and alternative names related to Obestatin
ghrelin (Ghrl), 2210006E23Rik, Ghr, m46, MTLRP, MTLRPAPProtein level used designations for Obestatin
- appetite-regulating hormone
- growth hormone secretagogue
- growth hormone-releasing peptide
- motilin-related peptide
- preproghrelin
- proghrelin
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