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O3FAR1 Products

(omega-3 Fatty Acid Receptor 1 (O3FAR1))
This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

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Featured O3FAR1 Categories

O3FAR1 Antibodies

High quality antibodies with extensive validation data.

O3FAR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

O3FAR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended O3FAR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (8)
Cat. No. ABIN2854731
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF, IHC
Validations
  • (7)
Cat. No. ABIN7074942
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS
Validations
  • (4)
Cat. No. ABIN7043397
Quantity 50 μL
Datasheet Datasheet

Recommended O3FAR1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6969052
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969051
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958300
Quantity 96 tests
Datasheet Datasheet

Recommended O3FAR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408696
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408693
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Mammalian Cells
Validations
Cat. No. ABIN7538454
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our O3FAR1 products

Bódis, Kahl, Simon, Zhou, Sell, Knebel, Tura, Strassburger, Burkart, Müssig, Markgraf, Al-Hasani, Szendroedi, Roden: "Reduced expression of stearoyl-CoA desaturase-1, but not free fatty acid receptor 2 or 4 in subcutaneous adipose tissue of patients with newly diagnosed type 2 diabetes mellitus." in: Nutrition & diabetes, Vol. 8, Issue 1, pp. 49, (2019) (PubMed).

Tsai, Li, Chang, Tey, Lin, Huang: "Long-Chain Fatty Acid Receptors Mediate Relaxation of the Porcine Lower Esophageal Sphincter." in: Frontiers in physiology, Vol. 10, pp. 676, (2019) (PubMed).

Kang, Huang, Lee, Jung, Im, Koh, Im: "Omega-3 polyunsaturated fatty acids protect human hepatoma cells from developing steatosis through FFA4 (GPR120)." in: Biochimica et biophysica acta, Vol. 1863, Issue 2, pp. 105-116, (2018) (PubMed).

Zhu, Lin, Song, Wu, Feng, Chen, He, Chen: "RA and ω-3 PUFA co-treatment activates autophagy in cancer cells." in: Oncotarget, Vol. 8, Issue 65, pp. 109135-109150, (2018) (PubMed).

Liu, Costanzo, Evans, Archer, Nowson, Duesing, Keast: "Expression of the candidate fat taste receptors in human fungiform papillae and the association with fat taste function." in: The British journal of nutrition, Vol. 120, Issue 1, pp. 64-73, (2018) (PubMed).

Chen, Zhang, Ho, Lin, Suen, Zhang, Zha, Li, Leung: "GPR120 is an important inflammatory regulator in the development of osteoarthritis." in: Arthritis research & therapy, Vol. 20, Issue 1, pp. 163, (2018) (PubMed).

Lee, Park, Kang, Koh, Sato, Chung, Okajima, Im: "ω-3 Polyunsaturated fatty acids accelerate airway repair by activating FFA4 in club cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 312, Issue 6, pp. L835-L844, (2017) (PubMed).

Houthuijzen, Oosterom, Hudson, Hirasawa, Daenen, McLean, Hansen, van Jaarsveld, Peeper, Jafari Sadatmand, Roodhart, van de Lest, Ulven, Ishihara, Milligan, Voest: "Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, Issue 5, pp. 2195-2209, (2017) (PubMed).

Meng, Yuan, Zhang, Zhang, Fu, Zhu, Shu, Wang, Gao, Xi, Sun, Zhang, Jiang, Wang: "Stearic acid suppresses mammary gland development by inhibiting PI3K/Akt signaling pathway through GPR120 in pubertal mice." in: Biochemical and biophysical research communications, Vol. 491, Issue 1, pp. 192-197, (2017) (PubMed).

Cheshmehkani, Senatorov, Dhuguru, Ghoneim, Moniri: "Free-fatty acid receptor-4 (FFA4) modulates ROS generation and COX-2 expression via the C-terminal β-arrestin phosphosensor in Raw 264.7 macrophages." in: Biochemical pharmacology, Vol. 146, pp. 139-150, (2017) (PubMed).

Synonyms and alternative names related to O3FAR1

free fatty acid receptor 4 (FFAR4), free fatty acid receptor 4 (Ffar4), phosphodiesterase 6C (PDE6C), AI552415, BMIQ10, GPR120, Gpr120, GPR129, Gpr129, GT01, KPG_013, O3FAR1, O3far1, PGR4, Pgr4

Protein level used designations for O3FAR1

  • G-protein coupled receptor 120
  • G-protein coupled receptor 129
  • G-protein coupled receptor GT01
  • G-protein coupled receptor PGR4
  • omega-3 fatty acid receptor 1
  • G protein-coupled receptor 120
  • G-protein-coupled receptor GT01
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