OAS1A Products
(2'-5' Oligoadenylate Synthetase 1A (OAS1A))
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This gene is a member of the 2'-5' oligoA synthetase family, which are clustered on chromosome 5. The encoded protein functions in the interferon-regulated OAS/RNase L system, which mediates RNA decay as part of the innate antiviral immunity pathway. The protein binds double-stranded RNA and oligomerizes ATP, which activate the single-stranded RNA cleavage enzyme RNase L. This protein mediates resistance to flaviviruses such as West Nile virus. The majority of wild mouse strains produce a functional protein and are resistant to flavivirus infection, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a premature stop codon that inactivates this gene product. [provided by RefSeq, Jul 2008].
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OAS1A Antibodies
High quality antibodies with extensive validation data.
OAS1A ELISA Kits
Reliable ELISA kits for a wide range of species.
OAS1A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended OAS1A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA, WB
Validations
Cat. No.
ABIN1175792
Quantity
200 μL
Datasheet
Datasheet
Recommended OAS1A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6953345
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6953347
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953346
Quantity
96 tests
Datasheet
Datasheet
Recommended OAS1A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3132884
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our OAS1A products
: "Preclinical evaluation of an O(6)-methylguanine-DNA methyltransferase-siRNA/liposome complex administered by convection-enhanced delivery to rat and porcine brains." in: American journal of translational research, Vol. 6, Issue 2, pp. 169-78, (2014) (PubMed).: "HCV NS5A and IRF9 compete for CypA binding." in: Journal of hepatology, Vol. 58, Issue 1, pp. 16-23, (2013) (PubMed).
: "Prevention of fatal and nonfatal ischemic heart disease by early treatment of hypertension." in: Cardiology, Vol. 72 Suppl 1, pp. 182-6, (1985) (PubMed).
Synonyms and alternative names related to OAS1A
2'-5' oligoadenylate synthetase 1A (Oas1a), 2'-5' oligoadenylate synthetase 1B (Oas1b), Flv, L1, L3, Mmu-L1, Oas1, Oas1g, Oias-2, Oias2, WnvProtein level used designations for OAS1A
- (2-5')oligo(A) synthase 1
- (2-5')oligo(A) synthase 1A
- (2-5')oligo(A) synthetase 1
- 2',5'-oligoadenylate synthetase 1, 40/46kDa
- 2'-5' oligoadenylate synthetase 1G
- 2'-5'-oligoadenylate synthase 1
- 2'-5'-oligoadenylate synthase 1A
- 2'-5'-oligoadenylate synthetase 1
- 2-5A synthase 1
- 2-5A synthase 1A
- 2-5A synthetase 1
- 25 oligoadenylate synthetase
- (2-5')oligo(A) synthetase 1A
- 2-5A synthetase 1A
- p42 OAS
- (2-5')oligo(A) synthase 1B
- (2-5')oligo(A) synthetase 1b
- 2',5'-oligoadenylate synthetase-like 1
- 2'-5'-oligoadenylate synthase 1B
- 2'-5'-oligoadenylate synthase-like protein 1
- 2'-5'-oligoadenylate synthetase-like protein 1
- 2-5A synthase 1B
- 2-5A synthetase 1B
- Flavivirus resistance
- inactive 2'-5'-oligoadenylate synthase 1B
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