NUP100 (nucleoporin 100kDa) (NUP100) Peptide
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- Target
- NUP100 (NUP100 (nucleoporin 100kDa) (NUP100))
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunocytochemistry (ICC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NUP50 antibody (Catalog #: ARP52288_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NUP100 (NUP100 (nucleoporin 100kDa) (NUP100))
- Synonyms
- NSP100 Peptide, Nucleoporin NUP100/NSP100 Peptide, NUP100 Peptide
- Background
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The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import.The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC39961, NPAP60, NPAP60L
Protein Interaction Partner: CDKN1B,KPNA2,KPNB1,RAN,XPO1,BTBD12,CDKN1B,IPO13,KPNA2,KPNB1,NUP153
Protein Size: 468 - Molecular Weight
- 50 kDa
- Gene ID
- 10762
- NCBI Accession
- NM_007172, NP_009103
- UniProt
- Q9UKX7
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