NUB1 Products
(Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
Categories
This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].
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Featured NUB1 Categories
NUB1 Antibodies
High quality antibodies with extensive validation data.
NUB1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NUB1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IHC, IHC (p), IF, FACS
Validations
- (7)
Cat. No.
ABIN1490743
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6263785
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN389078
Quantity
400 μL
Datasheet
Datasheet
Recommended NUB1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381369
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1144444
Quantity
96 tests
Datasheet
Datasheet
Recommended NUB1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313139
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313137
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3084737
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NUB1 products
: "Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 32905-13, (2003) (PubMed).: "The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1." in: Human molecular genetics, Vol. 11, Issue 22, pp. 2723-33, (2002) (PubMed).
: "NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 20603-9, (2001) (PubMed).
Synonyms and alternative names related to NUB1
negative regulator of ubiquitin-like proteins 1 (Nub1), negative regulator of ubiquitin like proteins 1 (NUB1), 4931404D21Rik, 6330412F12Rik, BS4, NUB1L, NY-REN-18, NYREN18Protein level used designations for NUB1
- NEDD8 ultimate buster 1
- NEDD8 ultimate buster-1
- NY-REN-18 antigen
- renal carcinoma antigen NY-REN-18
- Nedd8 ultimate buster-1
Did you look for something else?
- NUAK2
- NUAK1
- NTX-I
- NTSR2
- NTSR1
- NTRK3
- Nth Endonuclease III-Like 1
- NTAN1
- NTA1
- NT5M
- NT5DC4
- NT5DC3
- NT5C3L
- NT5C3
- NT5C1B
- NT5C1A
- NT5C
- NT-ProBNP
- NSUN7
- NSUN6
- Nubbin
- NUBP2
- NUBPL
- NUCB2
- NUCB2
- Nucleaoside Diphosphate Kinase
- Nuclear Antigen
- Nuclear Casein Kinase and Cyclin-Dependent Kinase Substrate 1
- Nuclear Factor 1
- Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha
- Nuclear LaMiN Family Member (Lmn-1)
- Nuclear Marker
- Nuclear Matrix Protein 22
- Nuclear Receptor Subfamily 1, Group D, Member 2
- Nuclear Receptor Subfamily 1, Group H, Member 2/3
- Nuclear Receptor Subfamily 2, Group C, Member 1
- Nuclear Transcription Factor Y, beta
- Nuclease
- Nuclease P1
- Nuclease S1
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