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NRF1 Products

(Nuclear Respiratory Factor 1 (NRF1))

Categories

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1. [provided by RefSeq, Jul 2008].

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Featured NRF1 Categories

NRF1 Antibodies

High quality antibodies with extensive validation data.

NRF1 ELISA Kits

Reliable ELISA kits for a wide range of species.

NRF1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NRF1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), RNAi
Validations
  • (1)
  • (7)
Cat. No. ABIN2752368
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC, IP
Validations
  • (2)
  • (8)
Cat. No. ABIN2855569
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p), ICC
Validations
  • (1)
  • (6)
Cat. No. ABIN3044020
Quantity 100 μg
Datasheet Datasheet

Recommended NRF1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958272
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958273
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648502
Quantity 96 tests
Datasheet Datasheet

Recommended NRF1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313021
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313019
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414915
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our NRF1 products

Mesquita, Lamb, Parry, Moore, Smith, Vann, Osburn, Fox, Ruple, Huggins, Fruge, Young, Kavazis, Roberts: "Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults." in: Physiological reports, Vol. 8, Issue 15, pp. e14526, (2020) (PubMed).

Ma, Cheng, Mu, Geng, Zhao, Luo, Ma, Chang, Liu, Gao, Nie, Xie, Han, Chen, Ma, Zhu, Chen: "The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression." in: Nature communications, Vol. 10, Issue 1, pp. 1034, (2019) (PubMed).

Hinkley, Morton, Ichinoseki-Sekine, Huertas, Smuder: "Exercise Training Prevents Doxorubicin-induced Mitochondrial Dysfunction of the Liver." in: Medicine and science in sports and exercise, Vol. 51, Issue 6, pp. 1106-1115, (2019) (PubMed).

Yamawaki-Ogata, Oshima, Usui, Narita: "Bone marrow-derived mesenchymal stromal cells regress aortic aneurysm via the NF-kB, Smad3 and Akt signaling pathways." in: Cytotherapy, Vol. 19, Issue 10, pp. 1167-1175, (2018) (PubMed).

Miura, Saitoh, Kokubun, Owada, Yamauchi, Machii, Takeishi: "Mitochondrial-Targeted Antioxidant Maintains Blood Flow, Mitochondrial Function, and Redox Balance in Old Mice Following Prolonged Limb Ischemia." in: International journal of molecular sciences, Vol. 18, Issue 9, (2018) (PubMed).

Roy, Pratheeshkumar, Son, Wang, Hitron, Divya, Zhang, Shi: "Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells." in: Toxicology and applied pharmacology, Vol. 307, pp. 81-90, (2016) (PubMed).

Suh, Chon, Choi: "Actein protects against methylglyoxal-induced oxidative damage in osteoblastic MC3T3-E1 cells." in: Journal of the science of food and agriculture, (2016) (PubMed).

Sun, Zhong, Zhang, Zhou: "Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction in a rat model of alcoholic liver disease: role of zinc deficiency." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 310, Issue 3, pp. G205-14, (2016) (PubMed).

Yan, Ji, Shi, Li, Sang: "Acute nitrogen dioxide inhalation induces mitochondrial dysfunction in rat brain." in: Environmental research, Vol. 138, pp. 416-24, (2015) (PubMed).

Li, Gao, Dong, Shi, Fang: "Icariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosis." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119955, (2015) (PubMed).

Synonyms and alternative names related to NRF1

nuclear respiratory factor 1 (NRF1), nuclear respiratory factor 1 (Nrf1), nuclear respiratory factor 1 (nrf1), nuclear respiratory factor 1 S homeolog (nrf1.S), ALPHA-PAL, alpha-pal, C87038, D6Ertd415e, IBR/F, LOC100220087, Nfe2l1_retired, nrf-1, NRF1, SC:BZ3C13.1, SC:bZ3C13.2, ube2h

Protein level used designations for NRF1

  • NRF-1
  • alpha palindromic-binding protein
  • alpha-pal
  • not really finished protein
  • nrf
  • nrf-1
  • nrl
  • nuclear respiratory factor-1
  • transcription factor
  • nuclear respiratory factor 1
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