NR1H2 Products
(Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
Categories
The liver X receptors, LXRA (NR1H3\; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs\; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010].
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Featured NR1H2 Categories
NR1H2 Antibodies
High quality antibodies with extensive validation data.
NR1H2 ELISA Kits
Reliable ELISA kits for a wide range of species.
NR1H2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NR1H2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC, IP
Validations
- (7)
Cat. No.
ABIN7444937
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, FACS
Validations
- (4)
Cat. No.
ABIN185293
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN521265
Quantity
100 μg
Datasheet
Datasheet
Recommended NR1H2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969009
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN579470
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN454778
Quantity
96 tests
Datasheet
Datasheet
Recommended NR1H2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312932
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7420831
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419373
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NR1H2 products
: "Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation." in: Genome medicine, Vol. 8, Issue 1, pp. 74, (2016) (PubMed).: "Complementary Cholesterol-Lowering Response of a Phytosterol/?-Lipoic Acid Combination in Obese Zucker Rats." in: Journal of dietary supplements, (2015) (PubMed).
: "Effect of garlic on lipid profile and expression of LXR alpha in intestine and liver of hypercholesterolemic mice." in: Journal of diabetes and metabolic disorders, Vol. 13, Issue 1, pp. 20, (2014) (PubMed).
: "Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation." in: Cell, Vol. 156, Issue 5, pp. 986-1001, (2014) (PubMed).
: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).
: "The probiotic Lactobacillus rhamnosus BFE5264 and Lactobacillus plantarum NR74 promote cholesterol efflux and suppress inflammation in THP-1 cells." in: Journal of the science of food and agriculture, Vol. 93, Issue 4, pp. 781-7, (2013) (PubMed).
: "Reduction in cholesterol absorption in Caco-2 cells through the down-regulation of Niemann-Pick C1-like 1 by the putative probiotic strains Lactobacillus rhamnosus BFE5264 and Lactobacillus plantarum ..." in: International journal of food sciences and nutrition, Vol. 64, Issue 1, pp. 44-52, (2013) (PubMed).
: "Lipocalin 2 deficiency alters estradiol production and estrogen receptor signaling in female mice." in: Endocrinology, Vol. 153, Issue 3, pp. 1183-93, (2012) (PubMed).
: "Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors." in: Placenta, Vol. 32, Issue 2, pp. 183-91, (2011) (PubMed).
: "Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease." in: PLoS ONE, Vol. 6, Issue 8, pp. e24293, (2011) (PubMed).
Synonyms and alternative names related to NR1H2
nuclear receptor subfamily 1 group H member 2 (NR1H2), nuclear receptor subfamily 1 group H member 2 (nr1h2), nuclear receptor subfamily 1, group H, member 2 (Nr1h2), nuclear receptor subfamily 1, group H, member 2 (NR1H2), nuclear receptor subfamily 1 group H member 2 L homeolog (nr1h2.L), AI194859, DKFZp468A0622, LXR, lxr-b, LXR-b, lxrb, LXRB, LXRbeta, ner, NER, ner-i, NER-I, NER1, NR1H2, OR-1, rip15, RIP15, unr, Unr, UNR, Unr2, URProtein level used designations for NR1H2
- nuclear receptor subfamily 1, group H, member 2
- LXR beta
- liver X receptor beta
- oxysterols receptor LXR-beta
- retinoid X receptor-interacting protein No.15
- ubiquitously-expressed nuclear receptor 2
- UR
- nuclear orphan receptor LXR-beta
- orphan nuclear receptor OR-1
- ubiquitous receptor
- ubiquitously-expressed nuclear receptor
- LX receptor beta
- liver X nuclear receptor beta
- nuclear receptor NER
- steroid hormone-nuclear receptor NER
- nuclear receptor subfamily 1 group H member 2
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