NR0B2 Products
(Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
Categories
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008].
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Featured NR0B2 Categories
NR0B2 Antibodies
High quality antibodies with extensive validation data.
NR0B2 ELISA Kits
Reliable ELISA kits for a wide range of species.
NR0B2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NR0B2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (5)
Cat. No.
ABIN3015601
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, FACS, IHC (p)
Validations
- (4)
Cat. No.
ABIN655027
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Rabbit
Application
WB, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN6741607
Quantity
100 μL
Datasheet
Datasheet
Recommended NR0B2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958250
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative
Validations
Cat. No.
ABIN627370
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative
Validations
Cat. No.
ABIN995938
Quantity
96 tests
Datasheet
Datasheet
Recommended NR0B2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312927
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413040
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418809
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NR0B2 products
: "Bile acid malabsorption is associated with diarrhea in acute phase of colitis." in: Canadian journal of physiology and pharmacology, Vol. 96, Issue 12, pp. 1328-1336, (2019) (PubMed).: "Raspberry pomace alters cecal microbial activity and reduces secondary bile acids in rats fed a high-fat diet." in: The Journal of nutritional biochemistry, Vol. 46, pp. 13-20, (2017) (PubMed).
: "The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3)." in: Molecular pharmacology, Vol. 82, Issue 5, pp. 918-28, (2012) (PubMed).
: "Epigenetic inhibition of nuclear receptor small heterodimer partner is associated with and regulates hepatocellular carcinoma growth." in: Gastroenterology, Vol. 134, Issue 3, pp. 793-802, (2008) (PubMed).
: "Cellular distributions of molecules with altered expression specific to the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model." in: Carcinogenesis, Vol. 29, Issue 11, pp. 2218-26, (2008) (PubMed).
: "Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well ..." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 10, pp. 2326-42, (2006) (PubMed).
Synonyms and alternative names related to NR0B2
nuclear receptor subfamily 0 group B member 2 (NR0B2), nuclear receptor subfamily 0, group B, member 2 (Nr0b2), nuclear receptor subfamily 0, group B, member 2a (nr0b2a), gb:bc058069, Nr0b2, NR0B2-A, SHP, Shp, SHP-1, SHP-A, SHP1, Shp1Protein level used designations for NR0B2
- short heterodimer partner
- nuclear receptor subfamily 0 group B member 2
- nuclear receptor SHP
- orphan nuclear receptor SHP
- small heterodimer partner
- small heterodimer partner homologue
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