NQO1 Products
(NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
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This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Featured NQO1 Categories
NQO1 Antibodies
High quality antibodies with extensive validation data.
NQO1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NQO1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NQO1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (2)
- (6)
Cat. No.
ABIN969319
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (6)
Cat. No.
ABIN6213595
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7430126
Quantity
100 μL
Datasheet
Datasheet
Recommended NQO1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958020
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958021
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6975559
Quantity
96 tests
Datasheet
Datasheet
Recommended NQO1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312919
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN668043
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7386197
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NQO1 products
: "Hesperetin modulates the Sirt1/Nrf2 signaling pathway in counteracting myocardial ischemia through suppression of oxidative stress, inflammation, and apoptosis." in: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Vol. 139, pp. 111552, (2021) (PubMed).: "Polysaccharides from Dendrobium officinale ameliorate colitis-induced lung injury via inhibiting inflammation and oxidative stress." in: Chemico-biological interactions, Vol. 347, pp. 109615, (2021) (PubMed).
: "p62/SQSTM1 and Nrf2 are essential for exercise-mediated enhancement of antioxidant protein expression in oxidative muscle." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 7, pp. 8022-8032, (2019) (PubMed).
: "Differential response to lead toxicity in rat primary microglia and astrocytes." in: Toxicology and applied pharmacology, Vol. 363, pp. 64-71, (2019) (PubMed).
: "Selenium Deficiency Is Associated with Pro-longevity Mechanisms." in: Cell reports, Vol. 27, Issue 9, pp. 2785-2797.e3, (2019) (PubMed).
: "Nrf2 antioxidant pathway suppresses Numb-mediated epithelial-mesenchymal transition during pulmonary fibrosis." in: Cell death & disease, Vol. 9, Issue 2, pp. 83, (2019) (PubMed).
: "Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway." in: Life sciences, Vol. 228, pp. 35-46, (2019) (PubMed).
: "The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues." in: Antioxidants (Basel, Switzerland), Vol. 6, Issue 4, (2018) (PubMed).
: "The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity." in: Nature communications, Vol. 9, Issue 1, pp. 2092, (2018) (PubMed).
: "Inflammation, oxidative stress, and higher expression levels of Nrf2 and NQO1 proteins in the airways of women chronically exposed to biomass fuel smoke." in: Molecular and cellular biochemistry, Vol. 447, Issue 1-2, pp. 63-76, (2018) (PubMed).
Synonyms and alternative names related to NQO1
NAD(P)H dehydrogenase, quinone 1 (nqo1), NAD(P)H quinone dehydrogenase 1 (NQO1), NAD(P)H dehydrogenase, quinone 1 (Bpet2092), NAD(P)H dehydrogenase, quinone 1 L homeolog (nqo1.L), NAD(P)H quinone dehydrogenase 1 (nqo1), NAD(P)H quinone dehydrogenase 1 (Nqo1), NAD(P)H dehydrogenase, quinone 1 (Nqo1), AV001255, DHQU, DIA4, Dia4, DTD, Dtd, NADPH-d, Nmo-1, Nmo1, NMOR1, Nmor1, NMORI, nqo1, Ox-1, Ox1, QR1, Qr1, wu:fb63c10, zgc:77191Protein level used designations for NQO1
- NAD(P)H dehydrogenase [quinone] 1
- NAD(P)H menadione oxidoreductase 1, dioxin-inducible
- NAD(P)H dehydrogenase, quinone 1
- DT-diaphorase
- DTD
- NAD(P)H:quinone oxidoreductase 1
- QR1
- azoreductase
- menadione reductase
- phylloquinone reductase
- quinone reductase 1
- nad(p)h dehydrogenase (quinone) 1
- NAD(P)H:Quinone acceptor oxidoreductase type 1
- NAD(P)H:menadione oxidoreductase 1
- NAD(P)H:quinone oxireductase
- diaphorase (NADH/NADPH) (cytochrome b-5 reductase)
- diaphorase-4
- dioxin-inducible 1
- Diaphorase (NADH/NADPH)
- NAD(P)H:menadione oxidoreductase
- NAD(P)H dehydrogenase (quinone)
- NAD(P)H menadione oxidoreductase 1, dioxin inducible
- diaphorase 4 (NADH/NADPH)
- nicotinamide adenine dinucleotide phosphate diaphorase
- diaphorase 4
- NAD(P)H: quinone oxidoreductase 1
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