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NPY Products

(Neuropeptide Y (NPY))
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. [provided by RefSeq, Nov 2009].

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Featured NPY Categories

NPY Antibodies

High quality antibodies with extensive validation data.

NPY ELISA Kits

Reliable ELISA kits for a wide range of species.

NPY Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NPY Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7432820
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN3017529
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (2)
Cat. No. ABIN562025
Quantity 100 μg
Datasheet Datasheet

Recommended NPY ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (9)
  • (1)
Cat. No. ABIN6958144
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958145
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6958146
Quantity 96 tests
Datasheet Datasheet

Recommended NPY Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124156
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312910
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312908
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NPY products

Kang, Lu, Yang, Ma, Chen, Chen, Xu, Zhou, Zhou, Feng: "Sevoflurane Induces Hippocampal Neuronal Apoptosis by Altering the Level of Neuropeptide Y in Neonatal Rats." in: Neurochemical research, Vol. 45, Issue 9, pp. 1986-1996, (2020) (PubMed).

Mandal, Briski: "Hindbrain dorsal vagal complex AMPK controls hypothalamic gluco-regulatory transmitter and counter-regulatory hormone responses to hypoglycemia." in: Brain research bulletin, Vol. 144, pp. 171-179, (2019) (PubMed).

Özkaramanlı Gür, Sağbaş, Akyüz, Güzel, Alpsoy, Güler: "Role of sympathetic cotransmitter galanin on autonomic balance in heart failure: an active player or a bystander?" in: Anatolian journal of cardiology, Vol. 18, Issue 4, pp. 281-288, (2019) (PubMed).

Cheng, Lin, Chen, Cheng, Su, Huang: "The Na+/H+-Exchanger NHE1 Regulates Extra- and Intracellular pH and Nimodipine-sensitive [Ca2+]i in the Suprachiasmatic Nucleus." in: Scientific reports, Vol. 9, Issue 1, pp. 6430, (2019) (PubMed).

Shakya, Shrestha, Briski: "Hindbrain 5'-Adenosine Monophosphate-activated Protein Kinase Mediates Short-term Food Deprivation Inhibition of the Gonadotropin-releasing Hormone-Luteinizing Hormone Axis: Role of Nitric Oxide." in: Neuroscience, Vol. 383, pp. 46-59, (2019) (PubMed).

Christenson Wick, Tetzlaff, Krook-Magnuson: "Novel long-range inhibitory nNOS-expressing hippocampal cells." in: eLife, Vol. 8, (2019) (PubMed).

Farias, Netto, Boritza, Bettini, Dâmaso, de Freitas: "Mechanisms of sustained long-term weight loss after RYGB: α-MSH is a key factor." in: Neuropeptides, Vol. 69, pp. 60-65, (2019) (PubMed).

Kontovounisios, Qiu, Rasheed, Darzi, Tekkis: "The role of neurotensin as a novel biomarker in the endoscopic screening of high-risk population for developing colorectal neoplasia." in: Updates in surgery, Vol. 69, Issue 3, pp. 397-402, (2018) (PubMed).

Mandal, Shrestha, Alenazi, Shakya, Alhamami, Briski: "Effects of estradiol on lactoprivic signaling of the hindbrain upon the contraregulatory hormonal response and metabolic neuropeptide synthesis in hypoglycemic female rats." in: Neuropeptides, Vol. 70, pp. 37-46, (2018) (PubMed).

Tam, Szanda, Drori, Liu, Cinar, Kashiwaya, Reitman, Kunos: "Peripheral cannabinoid-1 receptor blockade restores hypothalamic leptin signaling." in: Molecular metabolism, Vol. 6, Issue 10, pp. 1113-1125, (2018) (PubMed).

Synonyms and alternative names related to NPY

neuropeptide Y (Npy), neuropeptide Y (NPY), neuropeptide Y (npy), neuropeptide Y S homeolog (npy.S), neuropeptide Y L homeolog (npy.L), neuropeptide Y (LOC100533423), 0710005A05Rik, MGC86288, npy, NPY, NPY02, NPY1, npya, npyb, preproNPY, prepronpy, PYY4, pyy4, RATNPY, RATNPY02, si:dkey-22m8.5, xnpy

Protein level used designations for NPY

  • pro-neuropeptide Y
  • prepro-neuropeptide Y
  • neuropeptide Yb
  • pre-pro hormone
  • preproneuropeptide Y, preproNPY
  • neuropeptide Y
  • neuropeptide Ya
  • pro-neuropeptide Y preproprotein
  • Pro-neuropeptide Y
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