NPTX2 Products
(Neuronal Pentraxin II (NPTX2))
Categories
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009].
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Featured NPTX2 Categories
NPTX2 Antibodies
High quality antibodies with extensive validation data.
NPTX2 ELISA Kits
Reliable ELISA kits for a wide range of species.
NPTX2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NPTX2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN6242482
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN389175
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Zebrafish (Danio rerio)
Application
WB
Validations
- (2)
- (1)
Cat. No.
ABIN6746446
Quantity
100 μL
Datasheet
Datasheet
Recommended NPTX2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958131
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958132
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958133
Quantity
96 tests
Datasheet
Datasheet
Recommended NPTX2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312904
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7410661
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7389926
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NPTX2 products
: "Declining levels of functionally specialized synaptic proteins in plasma neuronal exosomes with progression of Alzheimer's disease." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 2, pp. 888-893, (2018) (PubMed).: "A DNA methylation prognostic signature of glioblastoma: identification of NPTX2-PTEN-NF-κB nexus." in: Cancer research, Vol. 73, Issue 22, pp. 6563-73, (2013) (PubMed).
: "Neuronal pentraxin II is highly upregulated in Parkinson's disease and a novel component of Lewy bodies." in: Acta neuropathologica, Vol. 115, Issue 4, pp. 471-8, (2008) (PubMed).
: "No association between the neuronal pentraxin II gene polymorphism and autism." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 31, Issue 4, pp. 940-3, (2007) (PubMed).
: "Quantitative analysis of NPTX2 hypermethylation is a promising molecular diagnostic marker for pancreatic cancer." in: Pancreas, Vol. 35, Issue 3, pp. e9-15, (2007) (PubMed).
: "Narp and NP1 form heterocomplexes that function in developmental and activity-dependent synaptic plasticity." in: Neuron, Vol. 39, Issue 3, pp. 513-28, (2003) (PubMed).
: "Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 22, pp. 14500-5, (2002) (PubMed).
: "Mints as adaptors. Direct binding to neurexins and recruitment of munc18." in: The Journal of biological chemistry, Vol. 275, Issue 51, pp. 39803-6, (2001) (PubMed).
: "Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2." in: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17786-92, (2000) (PubMed).
: "Narp, a novel member of the pentraxin family, promotes neurite outgrowth and is dynamically regulated by neuronal activity." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 8, pp. 2463-78, (1996) (PubMed).
Synonyms and alternative names related to NPTX2
neuronal pentraxin 2 (NPTX2), neuronal pentraxin 2 (Nptx2), neuronal pentraxin II (NPTX2), neuronal pentraxin 1 (NPTX1), neuronal pentraxin 2a (nptx2a), NARP, Narp, NP-II, NP2, np2, NPTX2, nptx2, p50Protein level used designations for NPTX2
- apexin
- neuronal activity-regulated pentaxin
- neuronal pentraxin-2
- NP-II
- neuro activity regulated petaxin
- neuronal pentraxin II
- NP2
- neuronal activity-regulated pentraxin
- neuronal pentraxin 2
- AM50
- acrosomal pentaxin-like protein p50
- narp
- neuronal pentraxin 2a
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