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NPR2 Products

(Natriuretic Peptide Receptor B/guanylate Cyclase B (Atrionatriuretic Peptide Receptor B) (NPR2))
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008].

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Featured NPR2 Categories

NPR2 Antibodies

High quality antibodies with extensive validation data.

NPR2 ELISA Kits

Reliable ELISA kits for a wide range of species.

NPR2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NPR2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
  • (1)
Cat. No. ABIN679778
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN562038
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN562037
Quantity 50 μL
Datasheet Datasheet

Recommended NPR2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968810
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968809
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958041
Quantity 96 tests
Datasheet Datasheet

Recommended NPR2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7491319
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312895
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312896
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NPR2 products

Li, Tang, Cai, Qiu, Lin, Zhu, Owusu, Guo: "CNP signal pathway up-regulated in rectum of depressed rats and the interventional effect of Xiaoyaosan." in: World journal of gastroenterology : WJG, Vol. 21, Issue 5, pp. 1518-30, (2015) (PubMed).

Kita, Nishizawa, Okuno, Tanaka, Yasui, Matsuda, Yamada, Shimomura: "Competitive binding of musclin to natriuretic peptide receptor 3 with atrial natriuretic peptide." in: The Journal of endocrinology, Vol. 201, Issue 2, pp. 287-95, (2009) (PubMed).

van den Akker: "Structural insights into the ligand binding domains of membrane bound guanylyl cyclases and natriuretic peptide receptors." in: Journal of molecular biology, Vol. 311, Issue 5, pp. 923-37, (2001) (PubMed).

Synonyms and alternative names related to NPR2

natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2), natriuretic peptide receptor 2 (Npr2), natriuretic peptide receptor 2 (NPR2), AMDM, ANPb, ANPRB, cn, GC-B, GC-B2, GC-B3, GUC2B, GUCY2B, mNPR-B, NPR-B, NPR2, NPRB, NPRBi, pwe

Protein level used designations for NPR2

  • natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • natriuretic peptide receptor 2
  • ANP-B
  • ANPR-B
  • NPR-B
  • Nppb receptor
  • atrial natriuretic peptide receptor 2
  • atrial natriuretic peptide receptor type B
  • guanylate cyclase B
  • guanylyl cyclase-B
  • natriuretic peptide receptor B type
  • GC-B
  • atrial natriuretic peptide B-type receptor
  • ANPRB
  • atrial natriuretic peptide receptor B
  • natriuretic peptide receptor-B
  • atrionatriuretic peptide receptor B
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