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NPPB Products

(Natriuretic Peptides B (NPPB))
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008].

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Featured NPPB Categories

NPPB Antibodies

High quality antibodies with extensive validation data.

NPPB ELISA Kits

Reliable ELISA kits for a wide range of species.

NPPB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NPPB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (7)
Cat. No. ABIN7445456
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (8)
Cat. No. ABIN3023136
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IP, ICC
Validations
  • (5)
Cat. No. ABIN7445450
Quantity 100 μL
Datasheet Datasheet

Recommended NPPB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975823
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN5591729
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5591727
Quantity 96 tests
Datasheet Datasheet

Recommended NPPB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1312892
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7319519
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420705
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our NPPB products

Marchenkova, Vilotti, Fabbretti, Nistri: "Brain natriuretic peptide constitutively downregulates P2X3 receptors by controlling their phosphorylation state and membrane localization." in: Molecular pain, Vol. 11, Issue 1, pp. 71, (2015) (PubMed).

Chiu, Chen, Su, Lee, Hsieh, Ho: "The arrhythmogenic effect of self-assembling nanopeptide hydrogel scaffolds on neonatal mouse cardiomyocytes." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 5, pp. 1065-73, (2014) (PubMed).

Vilotti, Marchenkova, Ntamati, Nistri: "B-type natriuretic peptide-induced delayed modulation of TRPV1 and P2X3 receptors of mouse trigeminal sensory neurons." in: PLoS ONE, Vol. 8, Issue 11, pp. e81138, (2013) (PubMed).

Shaw, Fildes, Pucha?ka, Basith, Yonan, Williams: "BNP directly immunoregulates the innate immune system of cardiac transplant recipients in vitro." in: Transplant immunology, Vol. 20, Issue 3, pp. 199-202, (2008) (PubMed).

Goetze, Jensen, Møller, Bendtsen, Rehfeld, Henriksen: "BNP and N-terminal proBNP are both extracted in the normal kidney." in: European journal of clinical investigation, Vol. 36, Issue 1, pp. 8-15, (2006) (PubMed).

Hoffmann, Brueckmann, Bertsch, Wiessner, Liebetrau, Lang, Haase, Borggrefe, Huhle: "Increased plasma levels of NT-proANP and NT-proBNP as markers of cardiac dysfunction in septic patients." in: Clinical laboratory, Vol. 51, Issue 7-8, pp. 373-9, (2005) (PubMed).

Hall: "Essential biochemistry and physiology of (NT-pro)BNP." in: European journal of heart failure, Vol. 6, Issue 3, pp. 257-60, (2004) (PubMed).

Cheng, Kazanagra, Garcia, Lenert, Krishnaswamy, Gardetto, Clopton, Maisel: "A rapid bedside test for B-type peptide predicts treatment outcomes in patients admitted for decompensated heart failure: a pilot study." in: Journal of the American College of Cardiology, Vol. 37, Issue 2, pp. 386-91, (2001) (PubMed).

Wiedemann, Jahn, Kellner: "Effects of natriuretic peptides upon hypothalamo-pituitary-adrenocortical system activity and anxiety behaviour." in: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, Vol. 108, Issue 1, pp. 5-13, (2000) (PubMed).

Bettencourt, Ferreira, Pardal-Oliveira, Pereira, Queirós, Araújo, Cerqueira-Gomes, Maciel: "Clinical significance of brain natriuretic peptide in patients with postmyocardial infarction." in: Clinical cardiology, Vol. 23, Issue 12, pp. 921-7, (2000) (PubMed).

Synonyms and alternative names related to NPPB

natriuretic peptide B (NPPB), natriuretic peptide B (Nppb), natriuretic peptide type B (Nppb), AA408272, Bnf, BNP, BNP1, NPPB

Protein level used designations for NPPB

  • gamma-brain natriuretic peptide
  • natriuretic peptides B
  • brain type natriuretic peptide
  • natriuretic peptide precursor B
  • natriuretic protein
  • brain natriuretic peptide
  • Brain natriuretic factor
  • iso-ANP
  • natriuretic peptide precursor type B
  • Gamma-brain natriuretic peptide
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