NPM1 Products
(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
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This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].
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Featured NPM1 Categories
NPM1 Antibodies
High quality antibodies with extensive validation data.
NPM1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NPM1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NPM1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (1)
- (6)
Cat. No.
ABIN562035
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), IP, FACS
Validations
- (2)
- (3)
Cat. No.
ABIN1737584
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7435076
Quantity
100 μL
Datasheet
Datasheet
Recommended NPM1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
Cat. No.
ABIN6574308
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975010
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380488
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended NPM1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
Cat. No.
ABIN1312882
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124224
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2130870
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NPM1 products
: "Optimized protocol for combined PALM-dSTORM imaging." in: Scientific reports, Vol. 8, Issue 1, pp. 8749, (2018) (PubMed).: "Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival." in: Theranostics, Vol. 8, Issue 16, pp. 4359-4371, (2018) (PubMed).
: "Effects of hepatitis C virus core protein and nonstructural protein 4B on the Wnt/β-catenin pathway." in: BMC microbiology, Vol. 17, Issue 1, pp. 124, (2017) (PubMed).
: "Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells." in: Blood, Vol. 125, Issue 22, pp. 3447-54, (2015) (PubMed).
: "iTRAQ-Based Quantitative Proteomic Analysis of Nasopharyngeal Carcinoma." in: Journal of cellular biochemistry, Vol. 116, Issue 7, pp. 1431-41, (2015) (PubMed).
: "Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway." in: Carcinogenesis, Vol. 35, Issue 12, pp. 2822-30, (2014) (PubMed).
: "Toponostics of invasive ductal breast carcinoma: combination of spatial protein expression imaging and quantitative proteome signature analysis." in: International journal of clinical and experimental pathology, Vol. 4, Issue 5, pp. 454-67, (2011) (PubMed).
: "The proteomics of colorectal cancer: identification of a protein signature associated with prognosis." in: PLoS ONE, Vol. 6, Issue 11, pp. e27718, (2011) (PubMed).
: "Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors." in: Journal of virology, Vol. 84, Issue 6, pp. 2719-31, (2010) (PubMed).
: "Patient-derived tumor-reactive antibodies as diagnostic markers for ovarian cancer." in: Gynecologic oncology, Vol. 115, Issue 1, pp. 112-20, (2009) (PubMed).
Synonyms and alternative names related to NPM1
nucleophosmin 1 (NPM1), nucleophosmin 1 (Npm1), nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog (npm1.L), nucleophosmin 1b (npm1b), Nucleophosmin (npm), nucleophosmin (NPM1), nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), Nucleoplasmin (Nlp), nucleophosmin 1a (npm1a), B23, B23NP, CG7917, CRP1, Crp1, Dmel\\CG7917, dNLP, dNLP-S, NO38, NPM, Npm, npm, npm1, npm4, p22, sb:cb487Protein level used designations for NPM1
- nucleolar protein NO38
- nucleophosmin
- nucleophosmin/nucleoplasmin family, member 1
- nucleolar phosphoprotein B23
- numatrin
- NPM
- nucleolar protein B23.1
- nucleophosmin 1
- nucleoplasmin
- nucleophosmin/nucleoplasmin, 4
- Nucleophosmin
- CG7917-PA
- CG7917-PB
- Nlp-PA
- Nlp-PB
- Nucleoplasmin-like
- chromatin decondensation protein 1
- nucleoplasmin-1
- nucleophosmin 1a (nucleolar phosphoprotein B23, numatrin)
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