NPC2 Products
(Niemann-Pick Disease, Type C2 (NPC2))
Categories
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008].
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Featured NPC2 Categories
NPC2 Antibodies
High quality antibodies with extensive validation data.
NPC2 ELISA Kits
Reliable ELISA kits for a wide range of species.
NPC2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NPC2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7261367
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN524004
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN524003
Quantity
50 μg
Datasheet
Datasheet
Recommended NPC2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958196
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951621
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951622
Quantity
96 tests
Datasheet
Datasheet
Recommended NPC2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312853
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312851
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7321066
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NPC2 products
: "Comparative analysis of the seminal plasma proteomes of oligoasthenozoospermic and normozoospermic men." in: Reproductive biomedicine online, Vol. 30, Issue 5, pp. 522-31, (2015) (PubMed).: "Pulmonary abnormalities in animal models due to Niemann-Pick type C1 (NPC1) or C2 (NPC2) disease." in: PLoS ONE, Vol. 8, Issue 7, pp. e67084, (2013) (PubMed).
: "Lung cancer signatures in plasma based on proteome profiling of mouse tumor models." in: Cancer cell, Vol. 20, Issue 3, pp. 289-99, (2011) (PubMed).
: "Use of narrow-range peptide IEF to improve detection of lung adenocarcinoma markers in plasma and pleural effusion." in: Proteomics, Vol. 9, Issue 13, pp. 3414-24, (2009) (PubMed).
: "Regulation of sterol transport between membranes and NPC2." in: Biochemistry, Vol. 47, Issue 42, pp. 11134-43, (2008) (PubMed).
: "Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop." in: The Journal of biological chemistry, Vol. 283, Issue 2, pp. 1064-75, (2008) (PubMed).
: "NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 40, pp. 15287-92, (2008) (PubMed).
: "HE1/NPC2 status in human reproductive tract and ejaculated spermatozoa: consequence of vasectomy." in: Molecular human reproduction, Vol. 12, Issue 7, pp. 461-8, (2006) (PubMed).
Synonyms and alternative names related to NPC2
NPC intracellular cholesterol transporter 2 (Npc2), NPC intracellular cholesterol transporter 2 (NPC2), Niemann-Pick disease, type C2 (npc2), 2700012J19Rik, AA408070, AU045843, cb292, CE1, EDDM1, EPI-1, HE1, re1, sb:cb292Protein level used designations for NPC2
- epididymal secretory protein E1
- mE1
- niemann Pick type C2 protein homolog
- Niemann-Pick disease type C2 protein
- epididymal protein 1
- human epididymis-specific protein 1
- tissue-specific secretory protein
- Niemann Pick type C2
- epididymal secretory protein 1
- EPV20
- 16 kDa secretory protein
- 16kDa secretory protein
- 16.5 kDa secretory protein
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