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NOTCH2 Proteins

(Notch 2 (NOTCH2))

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].

recommended

NOTCH2 Protein (His-Avi Tag,Biotin) (ABIN7275365)

NOTCH2 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

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recommended

NOTCH2 Protein (AA 26-530) (Fc Tag) (ABIN7013569)

NOTCH2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

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NOTCH2 Origin: Mouse Host: CHO Cells Recombinant >95 % (SDS-PAGE) SDS

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NOTCH2 Proteins by Origin

Find NOTCH2 Proteins for a variety of species such as anti-Human NOTCH2, anti-Mouse NOTCH2. The species listed below are among those available. Click on a link to go to the corresponding products.

NOTCH2 Proteins by Source

Here you will find NOTCH2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

NOTCH2 Proteins by Protein Type

Here you can find NOTCH2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

NOTCH2 Proteins by Application

Find NOTCH2 Proteins validated for a specific application such as SDS, WB, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

NOTCH2 Proteins by Biological Activity

Find NOTCH2 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular NOTCH2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

NOTCH2 Protein (His-Avi Tag,Biotin)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7275365

Quantity 100 μg

Datasheet Datasheet

NOTCH2 Protein (AA 26-530) (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7013569

Quantity 100 μg

Datasheet Datasheet

NOTCH2 Protein (AA 26-494, Extracellular Domain) (Fc Tag)

Reactivity Mouse

Source CHO Cells

Validations

Cat. No. ABIN1344244

Quantity 50 μg

Datasheet Datasheet

NOTCH2 Protein (AA 27-136) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1312811

Quantity 10 μg

Datasheet Datasheet

NOTCH2 Protein (His tag)

Reactivity Human

Source Human Cells

Validations

Cat. No. ABIN7319906

Quantity 50 μg

Datasheet Datasheet

NOTCH2 Protein (AA 2251-2466) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7409635

Quantity 100 μg

Datasheet Datasheet

NOTCH2 Protein (AA 26-294) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7423015

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our NOTCH2 Proteins

Fiorini, Merck, Wilson, Ferrero, Jiang, Koch, Auderset, Laurenti, Tacchini-Cottier, Pierres, Radtke, Luther, Macdonald: "Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7212-22, (2009) (PubMed).

Aliases for NOTCH2 Proteins

neurogenic locus notch homolog protein 2 (LOC581186) Proteins
notch 2 (NOTCH2) Proteins
notch 3 (notch3) Proteins
notch 2 (Notch2) Proteins
notch 2 (notch2) Proteins
AGS2 Proteins
AI853703 Proteins
HJCYS Proteins
hN2 Proteins
N2 Proteins
notch6 Proteins
sb:cb884 Proteins

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NOTCH2 Proteins by Origin

NOTCH2 Proteins by Source

NOTCH2 Proteins by Protein Type

NOTCH2 Proteins by Application

NOTCH2 Proteins by Biological Activity

Popular NOTCH2 Proteins

Latest Publications for our NOTCH2 Proteins

Aliases for NOTCH2 Proteins

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