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Notch1 Proteins

(Notch 1 (NOTCH1))
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. [provided by RefSeq, Jul 2008].
Notch1 Protein (AA 19-526) (His-Avi Tag) Notch1 Protein (AA 19-526) (His-Avi Tag) Notch1 Protein (AA 19-526) (His-Avi Tag) (ABIN7275363)

NOTCH1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Notch1 Protein (His-Avi Tag,Biotin) Notch1 Protein (His-Avi Tag,Biotin) Notch1 Protein (His-Avi Tag,Biotin) (ABIN7275364)

NOTCH1 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

Notch1 Protein (AA 19-488, Extracellular Domain) (Fc Tag) (ABIN1344230)

NOTCH1 Origin: Mouse Host: CHO Cells Recombinant >95 % (SDS-PAGE) SDS

Notch1 Proteins by Origin

Find Notch1 Proteins for a variety of species such as anti-Human Notch1, anti-Mouse Notch1. The species listed below are among those available. Click on a link to go to the corresponding products.

Notch1 Proteins by Source

Here you will find Notch1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Notch1 Proteins by Protein Type

Here you can find Notch1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Notch1 Proteins by Application

Find Notch1 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Notch1 Proteins by Biological Activity

Find Notch1 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Notch1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275363
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275364
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source CHO Cells
Validations
  • (1)
Cat. No. ABIN1344230
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320796
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124195
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7197217
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312809
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7013576
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7013490
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Notch1 Proteins

Fiorini, Merck, Wilson, Ferrero, Jiang, Koch, Auderset, Laurenti, Tacchini-Cottier, Pierres, Radtke, Luther, Macdonald: "Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7212-22, (2009) (PubMed).

Aliases for Notch1 Proteins

notch 1 (notch1) Proteins
fibropellin-1 (LOC100631526) Proteins
Notch homolog 1, translocation-associated (Drosophila) (NOTCH1) Proteins
notch 1 (NOTCH1) Proteins
Notch homolog 1, translocation-associated (NOTCH1) Proteins
notch 1 (Notch1) Proteins
notch 1 S homeolog (notch1.S) Proteins
9930111A19Rik Proteins
hn1 Proteins
hN1 Proteins
lin-12 Proteins
Mis6 Proteins
N1 Proteins
notch Proteins
NOTCH Proteins
notch-1 Proteins
notch1 Proteins
NOTCH1 Proteins
notch1-a Proteins
tan1 Proteins
TAN1 Proteins
Tan1 Proteins
xnotch Proteins
xnotch1 Proteins
xotch Proteins
Xotch Proteins
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