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Notch1 Proteins

(Notch 1 (NOTCH1))

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. [provided by RefSeq, Jul 2008].

recommended

Notch1 Protein (AA 19-526) (His-Avi Tag) (ABIN7275363)

NOTCH1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

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recommended

Notch1 Protein (His-Avi Tag,Biotin) (ABIN7275364)

NOTCH1 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

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NOTCH1 Origin: Mouse Host: CHO Cells Recombinant >95 % (SDS-PAGE) SDS

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Notch1 Proteins by Origin

Find Notch1 Proteins for a variety of species such as anti-Human Notch1, anti-Mouse Notch1. The species listed below are among those available. Click on a link to go to the corresponding products.

Notch1 Proteins by Source

Here you will find Notch1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Notch1 Proteins by Protein Type

Here you can find Notch1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Notch1 Proteins by Application

Find Notch1 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Notch1 Proteins by Biological Activity

Find Notch1 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Notch1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Notch1 Protein (AA 19-526) (His-Avi Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7275363

Quantity 100 μg

Datasheet Datasheet

Notch1 Protein (His-Avi Tag,Biotin)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7275364

Quantity 100 μg

Datasheet Datasheet

Notch1 Protein (AA 19-488, Extracellular Domain) (Fc Tag)

Reactivity Mouse

Source CHO Cells

Validations

Cat. No. ABIN1344230

Quantity 50 μg

Datasheet Datasheet

Notch1 Protein (His tag)

Reactivity Mouse

Source Human Cells

Validations

Cat. No. ABIN7320796

Quantity 50 μg

Datasheet Datasheet

Notch1 Protein (AA 2309-2555) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7124195

Quantity 50 μg

Datasheet Datasheet

Notch1 Protein (His tag)

Reactivity Mouse

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN7197217

Quantity 50 μg

Datasheet Datasheet

Notch1 Protein (AA 23-132) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1312809

Quantity 10 μg

Datasheet Datasheet

Notch1 Protein (AA 19-526) (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7013576

Quantity 100 μg

Datasheet Datasheet

Notch1 Protein (AA 19-526) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7013490

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our Notch1 Proteins

Fiorini, Merck, Wilson, Ferrero, Jiang, Koch, Auderset, Laurenti, Tacchini-Cottier, Pierres, Radtke, Luther, Macdonald: "Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7212-22, (2009) (PubMed).

Aliases for Notch1 Proteins

notch 1 (notch1) Proteins
fibropellin-1 (LOC100631526) Proteins
Notch homolog 1, translocation-associated (Drosophila) (NOTCH1) Proteins
notch 1 (NOTCH1) Proteins
Notch homolog 1, translocation-associated (NOTCH1) Proteins
notch 1 (Notch1) Proteins
notch 1 S homeolog (notch1.S) Proteins
9930111A19Rik Proteins
hn1 Proteins
hN1 Proteins
lin-12 Proteins
Mis6 Proteins
N1 Proteins
notch Proteins
NOTCH Proteins
notch-1 Proteins
notch1 Proteins
NOTCH1 Proteins
notch1-a Proteins
tan1 Proteins
TAN1 Proteins
Tan1 Proteins
xnotch Proteins
xnotch1 Proteins
xotch Proteins
Xotch Proteins

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Notch1 Proteins by Origin

Notch1 Proteins by Source

Notch1 Proteins by Protein Type

Notch1 Proteins by Application

Notch1 Proteins by Biological Activity

Popular Notch1 Proteins

Latest Publications for our Notch1 Proteins

Aliases for Notch1 Proteins

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