NONO Products
(Non-POU Domain Containing, Octamer-Binding (NONO))
Categories
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq, Feb 2009].
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Featured NONO Categories
NONO Antibodies
High quality antibodies with extensive validation data.
NONO ELISA Kits
Reliable ELISA kits for a wide range of species.
NONO Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NONO Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Dog, Human, Monkey, Mouse
Application
WB, IHC, IF, IHC (p)
Validations
- (11)
Cat. No.
ABIN1491072
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (18)
Cat. No.
ABIN1491073
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (10)
Cat. No.
ABIN6144713
Quantity
100 μL
Datasheet
Datasheet
Recommended NONO ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958220
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5657428
Quantity
96 tests
Datasheet
Datasheet
Recommended NONO Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312785
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409494
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094215
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NONO products
: "Human proteins that interact with RNA/DNA hybrids." in: Genome research, Vol. 28, Issue 9, pp. 1405-1414, (2018) (PubMed).: "A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell." in: The Journal of biological chemistry, Vol. 293, Issue 6, pp. 1933-1943, (2017) (PubMed).
: "p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation." in: Molecular and cellular biology, Vol. 35, Issue 7, pp. 1223-37, (2015) (PubMed).
: "Subnuclear re-localization of SOX10 and p54NRB correlates with a unique neurological phenotype associated with SOX10 missense mutations." in: Human molecular genetics, Vol. 24, Issue 17, pp. 4933-47, (2015) (PubMed).
: "Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly(ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation." in: Journal of cell science, Vol. 125, Issue Pt 19, pp. 4555-66, (2012) (PubMed).
: "PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks." in: Nucleic acids research, Vol. 40, Issue 20, pp. 10287-301, (2012) (PubMed).
: "NONO and RALY proteins are required for YB-1 oxaliplatin induced resistance in colon adenocarcinoma cell lines." in: Molecular cancer, Vol. 10, pp. 145, (2011) (PubMed).
: "Known turnover and translation regulatory RNA-binding proteins interact with the 3' UTR of SECIS-binding protein 2." in: RNA biology, Vol. 6, Issue 1, pp. 73-83, (2009) (PubMed).
: "TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 27, Issue 8, pp. 1760-7, (2007) (PubMed).
: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
Synonyms and alternative names related to NONO
non-POU domain containing octamer binding (NONO), non-POU domain containing, octamer-binding (NONO), non-POU domain containing, octamer-binding (Nono), non-POU domain containing, octamer binding L homeolog (nono.L), non-POU-domain-containing, octamer binding protein (Nono), AA407051, AV149256, NMT55, nmt55, nonA, NRB54, nrb54, P54, P54NRB, p54nrb, xp54nrbProtein level used designations for NONO
- 54 kDa nuclear RNA- and DNA-binding protein
- 55 kDa nuclear protein
- DNA-binding p52/p100 complex, 52 kDa subunit
- non-POU domain-containing octamer (ATGCAAAT) binding protein
- non-POU domain-containing octamer-binding protein
- p54(nrb)
- non-POU-domain-containing, octamer-binding protein
- 54 kD nuclear RNA-binding protein
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