NLRP4 Products
(NLR Family, Pyrin Domain Containing 4 (NLRP4))
Categories
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV\; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1\; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008].
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Featured NLRP4 Categories
NLRP4 Antibodies
High quality antibodies with extensive validation data.
Recommended NLRP4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (4)
Cat. No.
ABIN872353
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1538995
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN3032022
Quantity
0.4 mL
Datasheet
Datasheet
Recommended NLRP4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093984
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NLRP4 products
: "Detection of Exosomal PD-L1 RNA in Saliva of Patients With Periodontitis." in: Frontiers in genetics, Vol. 10, pp. 202, (2019) (PubMed).: "NLRP4 negatively regulates autophagic processes through an association with beclin1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 3, pp. 1646-55, (2011) (PubMed).
: "miR-155, a Modulator of FOXO3a Protein Expression, Is Underexpressed and Cannot Be Upregulated by Stimulation of HOZOT, a Line of Multifunctional Treg." in: PLoS ONE, Vol. 6, Issue 2, pp. e16841, (2011) (PubMed).
: "A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta." in: The Journal of biological chemistry, Vol. 277, Issue 38, pp. 35333-40, (2002) (PubMed).
Synonyms and alternative names related to NLRP4
NLR family pyrin domain containing 4 (NLRP4), NLR family, pyrin domain containing 4 (Nlrp4), CLR19.5, CT58, NALP4, Nalp4, Nlrp4e, PAN2, PYPAF4, RGD1563529, RNH2Protein level used designations for NLRP4
- NACHT, LRR and PYD containing protein 4
- NACHT, LRR and PYD domains-containing protein 4
- NACHT, leucine rich repeat and PYD containing 4
- PAAD and NACHT-containing protein 2
- PYRIN and NACHT-containing protein 2
- PYRIN-containing APAF1-like protein 4
- cancer/testis antigen 58
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4
- ribonuclease inhibitor 2
- NLR family, pyrin domain containing 4
- NLR family, pyrin domain containing 4E
- NACHT, LRR and PYD domains-containing protein 4-like
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