NLRP12 Products
(NLR Family, Pyrin Domain Containing 12 (NLRP12))
Categories
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013].
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Featured NLRP12 Categories
NLRP12 Antibodies
High quality antibodies with extensive validation data.
NLRP12 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NLRP12 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN657935
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN530067
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN3032015
Quantity
0.4 mL
Datasheet
Datasheet
Recommended NLRP12 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312665
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094027
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3131152
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NLRP12 products
: "NLRP3, NLRP12, and IFI16 Inflammasomes Induction and Caspase-1 Activation Triggered by Virulent HSV-1 Strains Are Associated With Severe Corneal Inflammatory Herpetic Disease." in: Frontiers in immunology, Vol. 10, pp. 1631, (2019) (PubMed).: "NLRP12 modulates host defense through IL-17A-CXCL1 axis." in: Mucosal immunology, (2015) (PubMed).
Synonyms and alternative names related to NLRP12
NLR family, pyrin domain containing 12 (Nlrp12), NLR family pyrin domain containing 12 (NLRP12), NACHT, LRR and PYD domains-containing protein 3 (LOC100018508), CLR19.3, FCAS2, Nalp12, NALP12, PAN6, PYPAF7, RNO, RNO2Protein level used designations for NLRP12
- NACHT, leucine rich repeat and PYD containing 12
- NLR family, pyrin domain containing 12
- PYRIN-containing APAF1-like protein 7
- NACHT, LRR and PYD domains-containing protein 12
- NLR family, pyrin domain containing 12, isoform 2
- monarch 1
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12
- regulated by nitric oxide
- NACHT, LRR and PYD containing protein 12
- monarch-1
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