NLRP1 Products
(NLR Family, Pyrin Domain Containing 1 (NLRP1))
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This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].
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NLRP1 Antibodies
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NLRP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended NLRP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN7268935
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7160821
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IHC (p)
Validations
- (2)
Cat. No.
ABIN214515
Quantity
0.05 mg
Datasheet
Datasheet
Recommended NLRP1 ELISA Kits
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Reactivity
Analytical Method
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Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
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Cat. No.
ABIN6968954
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974912
Quantity
96 tests
Datasheet
Datasheet
Recommended NLRP1 Proteins
Latest Publications for our NLRP1 products
: "Reduction of SIRT1 epigenetically upregulates NALP1 expression and contributes to neuropathic pain induced by chemotherapeutic drug bortezomib." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 292, (2019) (PubMed).: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).
: "Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination." in: Metabolic brain disease, (2019) (PubMed).
: "Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke." in: Journal of biophotonics, (2017) (PubMed).
: "NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model." in: Journal of neuroinflammation, Vol. 12, pp. 18, (2015) (PubMed).
: "Intermittent fasting attenuates inflammasome activity in ischemic stroke." in: Experimental neurology, Vol. 257, pp. 114-9, (2014) (PubMed).
: "Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke." in: Cell death & disease, Vol. 4, pp. e790, (2013) (PubMed).
: "NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1? processing via the NLRP1 inflammasome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 8, pp. 2952-6, (2013) (PubMed).
: "Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes." in: The Journal of allergy and clinical immunology, Vol. 127, Issue 3, pp. 806-14.e1-4, (2011) (PubMed).
: "Inflammasome mRNA expression in human monocytes during early septic shock." in: American journal of respiratory and critical care medicine, Vol. 177, Issue 9, pp. 983-8, (2008) (PubMed).
Synonyms and alternative names related to NLRP1
NLR family pyrin domain containing 1 (NLRP1), NLR family pyrin domain containing 1 (Nlrp1), CARD7, CIDED, CLR17.1, DEFCAP, DEFCAP-L/S, NAC, NALP1, PP1044, SLEV1, VAMAS1Protein level used designations for NLRP1
- NACHT, LRR and PYD containing protein 1
- NACHT, LRR and PYD domains-containing protein 1
- NACHT, leucine rich repeat and PYD (pyrin domain) containing 1
- NACHT, leucine rich repeat and PYD containing 1
- caspase recruitment domain protein 7
- caspase recruitment domain-containing protein 7
- death effector filament-forming Ced-4-like apoptosis protein
- nucleotide-binding domain and caspase recruitment domain
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1
- NLR family, pyrin domain containing 1
- NLR family pyrin domain containing 1
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