Nlgn4l antibody (C-Term)
NLGN4L
Reactivity: Mouse
IF/ICC, IHC, WB
Host: Mouse
Monoclonal
S98-7
unconjugated
-
- Target
- Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))
- Binding Specificity
- AA 782-945, C-Term
- Reactivity
- Mouse
- Host
- Mouse
- Clonality
- Monoclonal
- Application
- Immunofluorescence (fixed cells) (IF/ICC), Immunohistochemistry (IHC), Western Blotting (WB)
- Purpose
- Anti-Neuroligin-4 Mouse Monoclonal Antibody
- Specificity
- This antibody recognizes mouse Neuroligin-4. It does not cross-react with other Neuroligins.
- Cross-Reactivity
- Mouse, Rat
- Immunogen
- Fusion protein corresponding to aa 782-945 (intracellular C-terminus) of mouse Neuroligin-4.
- Clone
- S98-7
- Isotype
- IgG1
-
- Application Notes
-
Immunoblotting: use at 1-2 μg/mL. A band of ~125-130 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Enduser should determine optimal concentrations for their application. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Reconstitution
- Dilute in PBS or medium that is identical to that used in the assay system.
- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- This product is stable for at least one (1) year at -20°C.
-
- Target
- Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))
- Alternative Name
- Nlgn4l
- Synonyms
- NL-4 antibody, NL4 antibody, Nlgn4 antibody, Nlgn4x antibody, neuroligin 4-like antibody, Nlgn4l antibody
- Background
- Neuroligin 4-like,Cell surface protein involved in cell-cell-interactions. Plays a role in the formation or maintenance of synaptic junctions via its interactions (via the extracellular domains) with neurexin family members. Plays a role in synaptic signal transmission. {PubMed:18434543, PubMed:21282647}.,Neuroligin-4 is a neuronal cell surface protein and a member of the type-B carboxylesterase- lipase protein family. Members of this family may act as splice site-specific ligands for beta- neurexins and may be involved in the formation and remodeling of central nervous system synapses. Neuroligin-4 interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=Detected at glycinergic postsynapses in retina. Detected on dendritic spines on cultured neurons.,Neuroligin-4, NL-4
- UniProt
- B0F2B4
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