Homeobox Protein Nkx-2.4 (LOC105228315) Peptide
LOC105228315
Reactivity: Human
Host: Synthetic
WB
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- Target
- NKX21 (LOC105228315) (Homeobox Protein Nkx-2.4 (LOC105228315))
- Origin
- Human
- Source
- Synthetic
- Application
- Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NKX21 antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NKX21 (LOC105228315) (Homeobox Protein Nkx-2.4 (LOC105228315))
- Background
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This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
Alias Symbols: NKX2A, TITF1, TTF1
Protein Size: 371 - Molecular Weight
- 40 kDa
- Gene ID
- 7080
- NCBI Accession
- NP_003308
- UniProt
- P43699
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