Nkx2-2 Products
(NK2 Homeobox 2 (Nkx2-2))
Categories
The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor. [provided by RefSeq, Jul 2008].
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Featured Nkx2-2 Categories
Nkx2-2 Antibodies
High quality antibodies with extensive validation data.
Nkx2-2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Nkx2-2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN969550
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF, FACS, IHC, StM
Validations
- (4)
Cat. No.
ABIN6940202
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, StM
Validations
- (4)
Cat. No.
ABIN6940201
Quantity
100 μg
Datasheet
Datasheet
Recommended Nkx2-2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6225662
Quantity
96 tests
Datasheet
Datasheet
Recommended Nkx2-2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312624
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3084440
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3134034
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Nkx2-2 products
: "Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants. ..." in: Nature genetics, Vol. 46, Issue 2, pp. 136-43, (2014) (PubMed).: "Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet." in: Diabetes, Vol. 62, Issue 10, pp. 3500-13, (2013) (PubMed).
: "NKX2.2 is a useful immunohistochemical marker for Ewing sarcoma." in: The American journal of surgical pathology, Vol. 36, Issue 7, pp. 993-9, (2012) (PubMed).
: "Two novel determinants of etoposide resistance in small cell lung cancer." in: Cancer research, Vol. 71, Issue 14, pp. 4877-87, (2011) (PubMed).
: "Homeodomain transcription factor NKX2.2 functions in immature cells to control enteroendocrine differentiation and is expressed in gastrointestinal neuroendocrine tumors." in: Endocrine-related cancer, Vol. 16, Issue 1, pp. 267-79, (2009) (PubMed).
: "EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma." in: PLoS ONE, Vol. 3, Issue 4, pp. e1965, (2008) (PubMed).
: "Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells." in: Nature biotechnology, Vol. 24, Issue 11, pp. 1392-401, (2006) (PubMed).
: "Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling." in: Nature, Vol. 398, Issue 6728, pp. 622-7, (1999) (PubMed).
: "Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells." in: Development (Cambridge, England), Vol. 125, Issue 12, pp. 2213-21, (1998) (PubMed).
: "Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling." in: Cell, Vol. 90, Issue 1, pp. 169-80, (1997) (PubMed).
Synonyms and alternative names related to Nkx2-2
NK2 homeobox 2 S homeolog (nkx2-2.S), NK2 homeobox 2 (NKX2-2), NK2 homeobox 2 (Nkx2-2), NK2 homeobox 2a (nkx2.2a), id:ibd5090, nk2.2, NKX-2.2, Nkx-2.2, nkx2-2, nkx2-2-A, nkx2.2, NKX2.2, Nkx2.2, NKX2B, tinman, wu:fc83b01, XeNK-2, Xnkx2.2, zgc:136536Protein level used designations for Nkx2-2
- NK2 transcription factor related, locus 2
- homeobox protein XENK-2
- NK-2 homolog B
- NK2 transcription factor-like protein B
- homeobox protein NK-2 homolog B
- homeobox protein Nkx-2.2
- Drosophila NK2 transcription factor related, locus 2
- glycoprotein GP330, renal
- homeobox protein Nkx2-2
- homeobox protein NK-2 homolog B-A
- homeobox protein Nkx-2.2a
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