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NK2 Homeobox 5 Products

(NK2 Homeobox 5 (NKX2-5))

Categories

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

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Featured NK2 Homeobox 5 Categories

NK2 Homeobox 5 Antibodies

High quality antibodies with extensive validation data.

NK2 Homeobox 5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NK2 Homeobox 5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (6)
Cat. No. ABIN570994
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (5)
Cat. No. ABIN560515
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p), FACS
Validations
  • (5)
Cat. No. ABIN6243913
Quantity 200 μL
Datasheet Datasheet

Recommended NK2 Homeobox 5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1777308
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134033
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3084656
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NK2 Homeobox 5 products

Ja, Miao, Zhen Tee, Lim, Nandihalli, J A Ramachandra, Mehta, Shim: "iPSC-derived human cardiac progenitor cells improve ventricular remodelling via angiogenesis and interstitial networking of infarcted myocardium." in: Journal of cellular and molecular medicine, Vol. 20, Issue 2, pp. 323-32, (2016) (PubMed).

Ramachandra, Shim: "Evaluation of sarcomeric organization in human pluripotent stem cell-derived cardiomyocytes." in: Methods in molecular biology (Clifton, N.J.), Vol. 1299, pp. 161-6, (2015) (PubMed).

Costa, Lee, Furtado, Xin, Sparrow, Martinez, Dunwoodie, Kurtenbach, Mohun, Rosenthal, Harvey: "Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5." in: PLoS ONE, Vol. 6, Issue 9, pp. e24812, (2011) (PubMed).

Briggs, Takeda, Cuadra, Wakimoto, Marks, Walker, Seki, Oh, Lu, Sumners, Raizada, Horikoshi, Weinberg, Yasui, Ikeda, Chien, Kasahara: "Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects." in: Circulation research, Vol. 103, Issue 6, pp. 580-90, (2008) (PubMed).

Yadava, Frenzel-McCardell, Yu, Srinivasan, Tucker, Puymirat, Thornton, Prall, Harvey, Mahadevan: "RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression." in: Nature genetics, Vol. 40, Issue 1, pp. 61-8, (2007) (PubMed).

Brewer, Alexandrovich, Mjaatvedt, Shah, Patient, Pizzey: "GATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesis." in: Stem cells and development, Vol. 14, Issue 4, pp. 425-39, (2005) (PubMed).

Ikeda, Hiroi, Hosoda, Utsunomiya, Matsuo, Ito, Inoue, Sumiyoshi, Takano, Nagai, Komuro: "Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 66, Issue 6, pp. 561-3, (2002) (PubMed).

Synonyms and alternative names related to NK2 Homeobox 5

NK2 homeobox 5 (NKX2-5), NK2 homeobox 5 (Nkx2-5), NK2 homeobox 5 (nkx2.5), NK2 homeobox 5 S homeolog (nkx2-5.S), NK2 homeobox 5 (nkx2-5), AR2, CHNG5, CNKX-2.5, CSX, Csx, csx, CSX1, csx1, HLHS2, nk2.5, Nkx-2.5, nkx-2.5, NKX-2.5, nkx2-5, NKX2-5, Nkx2-5, nkx2-5b, NKX2.5, Nkx2.5, nkx2.5, NKX2E, nkx2e, NKX4-1, tinman, VSD3, XNkx-2.5, XNkx2-5, zgc:111912

Protein level used designations for NK2 Homeobox 5

  • NK2 transcription factor related, locus 5
  • cardiac-specific homeobox 1
  • homeobox protein CSX
  • homeobox protein NK-2 homolog E
  • homeobox protein Nkx-2.5
  • tinman paralog
  • Drosophila NK2 transcription factor related, locus 5
  • cardiac-specific homeobox
  • tinman homeobox homolog
  • rNKx-2.5
  • NK2 transcription factor related 5 b
  • XNkx-2.5
  • NK2 transcription factor related, locus 5 (Drosophila)
  • transcription factor NKX2.5
  • NK2 transcription factor locus 5-like
  • Nkx2.5 protein
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