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Niemann-Pick Disease, Type C1 Proteins

(Niemann-Pick Disease, Type C1 (NPC1))

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009].

recommended

NPC1 Protein (AA 151-250) (GST tag) (ABIN1312849)

NPC1 Origin: Human Host: Wheat germ Recombinant WB, AP, AA, ELISA

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recommended

NPC1 Protein (His tag,DYKDDDDK Tag) (ABIN7317151)

NPC1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.

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recommended

NPC1 Protein (ABIN2750647)

NPC1 Origin: Human, Mouse, Rat Host: Escherichia coli (E. coli) Recombinant WB, PC

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Niemann-Pick Disease, Type C1 Proteins by Origin

Find Niemann-Pick Disease, Type C1 Proteins for a variety of species such as anti-Human Niemann-Pick Disease, Type C1, anti-Mouse Niemann-Pick Disease, Type C1, anti-Rat Niemann-Pick Disease, Type C1. The species listed below are among those available. Click on a link to go to the corresponding products.

Niemann-Pick Disease, Type C1 Proteins by Source

Here you will find Niemann-Pick Disease, Type C1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Niemann-Pick Disease, Type C1 Proteins by Protein Type

Here you can find Niemann-Pick Disease, Type C1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Niemann-Pick Disease, Type C1 Proteins by Application

Find Niemann-Pick Disease, Type C1 Proteins validated for a specific application such as WB, AP, AA, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Niemann-Pick Disease, Type C1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

NPC1 Protein (AA 151-250) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1312849

Quantity 10 μg

Datasheet Datasheet

NPC1 Protein (His tag,DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7317151

Quantity 100 μg

Datasheet Datasheet

NPC1 Protein

Reactivity Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2750647

Quantity 5 applications

Datasheet Datasheet

Aliases for Niemann-Pick Disease, Type C1 Proteins

NPC intracellular cholesterol transporter 1 (NPC1) Proteins
NPC1 like intracellular cholesterol transporter 1 (Npc1l1) Proteins
NPC intracellular cholesterol transporter 1 (Npc1) Proteins
Niemann-Pick disease, type C1 (npc1) Proteins
Niemann-Pick C1 protein (LOC579887) Proteins
9130221N23Rik Proteins
A430089E03Rik Proteins
C85354 Proteins
Cdig2 Proteins
D18Ertd139e Proteins
D18Ertd723e Proteins
Gm243 Proteins
im:7149020 Proteins
lcsd Proteins
nmf164 Proteins
NPC Proteins
spm Proteins
wu:fb53a12 Proteins
wu:fc29a12 Proteins

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Niemann-Pick Disease, Type C1 Proteins by Origin

Niemann-Pick Disease, Type C1 Proteins by Source

Niemann-Pick Disease, Type C1 Proteins by Protein Type

Niemann-Pick Disease, Type C1 Proteins by Application

Popular Niemann-Pick Disease, Type C1 Proteins

Aliases for Niemann-Pick Disease, Type C1 Proteins

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