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Nicastrin Proteins

(Nicastrin (NCSTN))

This gene encodes a Type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease\; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Alternatively spliced transcript variants have been described, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].

recommended

Nicastrin Protein (NCSTN) (AA 1-689) (GST tag) (ABIN1312150)

NCSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

Nicastrin Protein (NCSTN) (AA 16-115) (GST tag) (ABIN1312152)

NCSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

Nicastrin Protein (NCSTN) (His tag) (ABIN7320108)

NCSTN Origin: Mouse Host: HEK-293 Cells Recombinant > 99 % as determined by SDS-PAGE

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Nicastrin Proteins by Origin

Find Nicastrin Proteins for a variety of species such as anti-Human Nicastrin, anti-Mouse Nicastrin, anti-Rat Nicastrin. The species listed below are among those available. Click on a link to go to the corresponding products.

Nicastrin Proteins by Source

Here you will find Nicastrin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Nicastrin Proteins by Protein Type

Here you can find Nicastrin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Nicastrin Proteins by Application

Find Nicastrin Proteins validated for a specific application such as WB, ELISA, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Nicastrin Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Nicastrin Protein (NCSTN) (AA 1-689) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1312150

Quantity 10 μg

Datasheet Datasheet

Nicastrin Protein (NCSTN) (AA 16-115) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1312152

Quantity 10 μg

Datasheet Datasheet

Nicastrin Protein (NCSTN) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7320108

Quantity 100 μg

Datasheet Datasheet

Nicastrin Protein (NCSTN) (Fc Tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7320109

Quantity 100 μg

Datasheet Datasheet

Nicastrin Protein (NCSTN) (AA 420-655) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7405702

Quantity 100 μg

Datasheet Datasheet

Nicastrin Protein (NCSTN) (AA 35-534) (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417279

Quantity 100 μg

Datasheet Datasheet

Nicastrin Protein (NCSTN) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7197196

Quantity 50 μg

Datasheet Datasheet

Nicastrin Protein (NCSTN) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2727295

Quantity 20 μg

Datasheet Datasheet

Nicastrin Protein (NCSTN) (AA 35-668) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1613731

Quantity 1 mg

Datasheet Datasheet

Aliases for Nicastrin Proteins

nicastrin (NCSTN) Proteins
nicastrin (nct) Proteins
nicastrin (ncstn) Proteins
nicastrin (CpipJ_CPIJ001617) Proteins
nicastrin (Ncstn) Proteins
Nicastrin (aph-2) Proteins
9430068N19Rik Proteins
AA727311 Proteins
agro Proteins
APH2 Proteins
Aph2 Proteins
CG7012 Proteins
D1Dau13e Proteins
DKFZp469O2418 Proteins
Dmel\\CG7012 Proteins
dNct Proteins
Kiaa0253 Proteins
mKIAA0253 Proteins
NCSTN Proteins
Nct Proteins
Nic Proteins
nic Proteins
S5A Proteins
ST96B Proteins

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Nicastrin Proteins by Origin

Nicastrin Proteins by Source

Nicastrin Proteins by Protein Type

Nicastrin Proteins by Application

Popular Nicastrin Proteins

Aliases for Nicastrin Proteins

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