NGEF Products
(Neuronal Guanine Nucleotide Exchange Factor (NGEF))
Categories
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
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Featured NGEF Categories
NGEF Antibodies
High quality antibodies with extensive validation data.
NGEF ELISA Kits
Reliable ELISA kits for a wide range of species.
NGEF Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NGEF Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN1327160
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7151823
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6243777
Quantity
200 μL
Datasheet
Datasheet
Recommended NGEF ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1132027
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1132029
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1132028
Quantity
96 tests
Datasheet
Datasheet
Recommended NGEF Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312527
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094103
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136476
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to NGEF
neuronal guanine nucleotide exchange factor (NGEF), neuronal guanine nucleotide exchange factor (Ngef), ARHGEF27, Besh3, EPHEXIN, ephexin, Ephexin-1, ephexin-1, Tims2Protein level used designations for NGEF
- neuronal guanine nucleotide exchange factor
- ephexin-1
- eph-interacting exchange protein
- ephexin-1-like
- transforming immortalised mammary epithelial sequence 2
- brain-enriched SH3-domain protein Besh3
- ephexin1
- guanine nucleotide exchange factor
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