NFKB1 Products
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Categories
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
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Featured NFKB1 Categories
NFKB1 Antibodies
High quality antibodies with extensive validation data.
NFKB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NFKB1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NFKB1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (2)
- (7)
- (1)
Cat. No.
ABIN6144571
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), PLA
Validations
- (7)
- (1)
Cat. No.
ABIN561981
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, ChIP
Validations
- (6)
Cat. No.
ABIN7161781
Quantity
100 μg
Datasheet
Datasheet
Recommended NFKB1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6962926
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6962280
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6963203
Quantity
96 tests
Datasheet
Datasheet
Recommended NFKB1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1312483
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124203
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124204
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our NFKB1 products
: "Role of TRPV1/TRPV3 channels in olanzapine-induced metabolic alteration: Possible involvement in hypothalamic energy-sensing, appetite regulation, inflammation and mesolimbic pathway." in: Toxicology and applied pharmacology, Vol. 402, pp. 115124, (2021) (PubMed).: "Protective effect of apigenin magnesium complex on H2O2-induced oxidative stress and inflammatory responses in rat hepatic stellate cells." in: Pharmaceutical biology, Vol. 58, Issue 1, pp. 553-560, (2020) (PubMed).
: "Serum TLR9 and NF-κB Biochemical Markers in Patients with Acute Pancreatitis on Admission." in: Emergency medicine international, Vol. 2020, pp. 1264714, (2020) (PubMed).
: "Protective effect of oleuropein on ketamine-induced cardiotoxicity in rats." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 393, Issue 9, pp. 1691-1699, (2020) (PubMed).
: "Frequent exposure to varied home cage sizes alters pain sensitivity and some key inflammation-related biomarkers." in: Journal of neuroscience methods, Vol. 345, pp. 108890, (2020) (PubMed).
: "The Ying and Yang of Adenosine A1 and A2A Receptors on ERK1/2 Activation in a Rat Model of Global Cerebral Ischemia Reperfusion Injury." in: Molecular neurobiology, Vol. 55, Issue 2, pp. 1284-1298, (2019) (PubMed).
: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
: "IP-10 Promotes Blood-Brain Barrier Damage by Inducing Tumor Necrosis Factor Alpha Production in Japanese Encephalitis." in: Frontiers in immunology, Vol. 9, pp. 1148, (2018) (PubMed).
: "Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway." in: Biomedicine & pharmacotherapy, Vol. 107, pp. 793-805, (2018) (PubMed).
: "Goniothalamin induces cell cycle arrest and apoptosis in H400 human oral squamous cell carcinoma: A caspase-dependent mitochondrial-mediated pathway with downregulation of NF-κβ." in: Archives of oral biology, Vol. 64, pp. 28-38, (2017) (PubMed).
Synonyms and alternative names related to NFKB1
SCY1 like pseudokinase 1 (SCYL1), nuclear factor kappa B subunit 1 (NFKB1), nuclear factor kappa B subunit 1 (Nfkb1), nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog (nfkb1.L), nuclear factor NF-kappa-B p105 subunit (CpipJ_CPIJ012236), nucleoporin 107 (Nup107), nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Nfkb1), nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (nfkb1), BICDR-1, bicdr1, ccdc64, EBP-1, ebp-1, GKLP, KBF1, kbf1, NF-kappa-B, nf-kappa-b, NF-kappaB, nf-kappaB, NF-kappaB1, NF-kB, NF-kB1, NF-KB1, NFkappaB, NFKB-p50, nfkb-p50, NFKB-p105, nfkb-p105, NKTL, NTKL, p50, p50/p105, P105, p105, TAPK, TEIF, TRAPProtein level used designations for NFKB1
- N-terminal kinase-like protein
- SCY1-like protein 1
- coated vesicle-associated kinase of 90 kDa
- likely ortholog of mouse N-terminal kinase-like protein
- telomerase regulation-associated protein
- telomerase transcriptional element-interacting factor
- telomerase transcriptional elements-interacting factor
- teratoma-associated tyrosine kinase
- DNA binding factor KBF1
- DNA-binding factor KBF1
- NF-kappabeta
- nuclear factor NF-kappa-B p105 subunit
- nuclear factor NF-kappa-B p50 subunit
- nuclear factor kappa-B DNA binding subunit
- nuclear factor of kappa light chain gene enhancer in B-cells 1, p105
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
- NF-kB p50 subunit
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
- nuclear factor kappa-B, subunit 1
- nuclear factor of kappa light polypeptide enhancer in B-cells 1
- nuclear factor kappa-B 1
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- nuclear factor NF-kappa-B p105 subunit-like
- 107 kDa nucleoporin
- nuclear pore complex protein Nup107
- nucleoporin Nup107
- p105
- EBP-1
- NF kappaB1
- NF-kappa-B1 p84/NF-kappa-B1 p98
- NF-kappaB p50
- nuclear factor kappaB p50
- nuclear factor-kappaB p50
- p50 subunit of NF kappaB
- p50 subunit of NF-kappaB
- BICD-related protein 1
- NF-kB1 precursor protein
- bicaudal D-related protein 1
- coiled-coil domain-containing protein 64A
- p50
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