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NFE2 Products

(Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Categories

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

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Featured NFE2 Categories

NFE2 Antibodies

High quality antibodies with extensive validation data.

NFE2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NFE2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN518314
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IP, ICC, ChIP-seq
Validations
  • (3)
Cat. No. ABIN2855460
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN657484
Quantity 400 μL
Datasheet Datasheet

Recommended NFE2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312453
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312455
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3084480
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NFE2 products

Park, Jung, Kong, Park, Cheon, Choi: "Identification of OCTN2 variants and their association with phenotypes of Crohn's disease in a Korean population." in: Scientific reports, Vol. 6, pp. 22887, (2016) (PubMed).

Ikeda, Pak, Chavez, Ryan: "Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells." in: Molecular neurobiology, Vol. 51, Issue 2, pp. 672-84, (2015) (PubMed).

Synonyms and alternative names related to NFE2

nuclear factor, erythroid 2 (NFE2), nuclear factor, erythroid derived 2 (Nfe2), nuclear factor, erythroid 2 (Nfe2), 45kDa, NF-E2, p45, p45nf-e2, p45NFE2

Protein level used designations for NFE2

  • leucine zipper protein NF-E2
  • nuclear factor, erythroid derived 2
  • nuclear factor, erythroid-derived 2 45 kDa subunit
  • p45 NF-E2
  • transcription factor NF-E2 45 kDa subunit
  • nuclear factor (erythroid-derived 2), 45kD
  • nuclear factor (erythroid-derived 2), 45kDa
  • nuclear factor, erythroid derived 2, 45 kDa
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