NFAT1 Products
(Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
Categories
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012].
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Featured NFAT1 Categories
NFAT1 Antibodies
High quality antibodies with extensive validation data.
NFAT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NFAT1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NFAT1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN571020
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN6972419
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6748576
Quantity
100 μL
Datasheet
Datasheet
Recommended NFAT1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6958239
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5657453
Quantity
96 tests
Datasheet
Datasheet
Recommended NFAT1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312443
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409788
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094115
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NFAT1 products
: "The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease." in: Pediatric rheumatology online journal, Vol. 18, Issue 1, pp. 23, (2020) (PubMed).: "STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension." in: Hypertension (Dallas, Tex. : 1979), Vol. 71, Issue 3, pp. 518-529, (2018) (PubMed).
: "The protective effects of PCPA against monocrotaline-induced pulmonary arterial hypertension are mediated through the downregulation of NFAT-1 and NF-κB." in: International journal of molecular medicine, Vol. 40, Issue 1, pp. 155-163, (2018) (PubMed).
: "NFATc2 is an intrinsic regulator of melanoma dedifferentiation." in: Oncogene, Vol. 35, Issue 22, pp. 2862-72, (2016) (PubMed).
: "Mesenchymal stem cell-conditioned media suppresses inflammation-associated overproliferation of pulmonary artery smooth muscle cells in a rat model of pulmonary hypertension." in: Experimental and therapeutic medicine, Vol. 11, Issue 2, pp. 467-475, (2016) (PubMed).
: "The calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells." in: Cell death & disease, Vol. 6, pp. e1658, (2015) (PubMed).
: "Galanin modulates the neural niche to favour perineural invasion in head and neck cancer." in: Nature communications, Vol. 6, pp. 6885, (2015) (PubMed).
: "Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat." in: Circulation research, Vol. 116, Issue 10, pp. 1680-90, (2015) (PubMed).
: "NFAT targets signaling molecules to gene promoters in pancreatic β-cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 29, Issue 2, pp. 274-88, (2015) (PubMed).
: "Inhibition of interleukin-2 gene expression by human herpesvirus 6B U54 tegument protein." in: Journal of virology, Vol. 88, Issue 21, pp. 12452-63, (2014) (PubMed).
Synonyms and alternative names related to NFAT1
nuclear factor of activated T-cells 2 (NFATC2), nuclear factor of activated T-cells 2 (nfatc2), nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 (Nfatc2), nuclear factor of activated T-cells 2 (Nfatc2), AI607462, NF-ATc2, NFAT1, NFAT1-D, NFATC2, Nfatp, NFATPProtein level used designations for NFAT1
- nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
- nuclear factor of activated T-cells, cytoplasmic 2-like
- NF-ATp
- NFAT pre-existing subunit
- T-cell transcription factor NFAT1
- nuclear factor of activated T-cells, cytoplasmic 2
- NF-ATc2
- NFAT transcription complex, preexisting component
- T cell transcription factor NFAT1
- nuclear factor of activated T-cells, preexisting component
- preexisting nuclear factor of activated T-cells 2
Did you look for something else?
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- Neurotrophin 1
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