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Neurogranin Products

(Neurogranin (NRGN))
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008].

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Featured Neurogranin Categories

Neurogranin Antibodies

High quality antibodies with extensive validation data.

Neurogranin ELISA Kits

Reliable ELISA kits for a wide range of species.

Neurogranin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Neurogranin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN571065
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7425839
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7000018
Quantity 20 μL
Datasheet Datasheet

Recommended Neurogranin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6958115
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6958116
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958117
Quantity 96 tests
Datasheet Datasheet

Recommended Neurogranin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1313028
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124151
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7390334
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Neurogranin products

Abner, Jicha, Shaw, Trojanowski, Goetzl: "Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging." in: Annals of clinical and translational neurology, Vol. 3, Issue 5, pp. 399-403, (2016) (PubMed).

Winston, Goetzl, Akers, Carter, Rockenstein, Galasko, Masliah, Rissman: "Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile." in: Alzheimer's & dementia (Amsterdam, Netherlands), Vol. 3, pp. 63-72, (2016) (PubMed).

Goetzl, Kapogiannis, Schwartz, Lobach, Goetzl, Abner, Jicha, Karydas, Boxer, Miller: "Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 12, pp. 4141-4148, (2016) (PubMed).

Skelding, Suzuki, Gordon, Xue, Verrills, Dickson, Rostas: "Regulation of CaMKII by phospho-Thr253 or phospho-Thr286 sensitive targeting alters cellular function." in: Cellular signalling, Vol. 22, Issue 5, pp. 759-69, (2010) (PubMed).

Synonyms and alternative names related to Neurogranin

neurogranin (NRGN), neurogranin (Nrgn), neurogranin (protein kinase C substrate, RC3) b (nrgnb), 0710001B06Rik, AI838505, hng, NG, NG/RC3, Pss1, R75334, RC3, zgc:158686

Protein level used designations for Neurogranin

  • calmodulin-binding protein
  • neurogranin
  • ng
  • protein kinase C substrate
  • neurogranin (protein kinase C substrate, RC3)
  • postsynaptic spine 1
  • protein kinase C substrate 7.5 kDa protein
  • B-50 immunoreactive C-kinase substrate
  • BICKS
  • NG
  • p17
  • protein kinase C substrate, RC3
  • neurogranin (protein kinase C substrate, RC3) b
  • spa17
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