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Neurexin 1 Products

(Neurexin 1 (NRXN1))
Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human (NRXN1 and NRXN3). By using alternate promoters, splice sites and exons, predictions of hundreds or even thousands of distinct mRNAs have been made. Most transcripts use the upstream promoter and encode alpha-neurexin isoforms\; fewer transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. Alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible. [provided by RefSeq, Oct 2008].

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Featured Neurexin 1 Categories

Neurexin 1 Antibodies

High quality antibodies with extensive validation data.

Neurexin 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Neurexin 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Neurexin 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7161217
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (3)
Cat. No. ABIN190771
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6263607
Quantity 100 μL
Datasheet Datasheet

Recommended Neurexin 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN2748415
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5593130
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385252
Quantity 96 tests
Datasheet Datasheet

Recommended Neurexin 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124142
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313052
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2727116
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Neurexin 1 products

Zhao, Sharfman, Jaber, Lukiw et al.: "Down-Regulation of Essential Synaptic Components by GI-Tract Microbiome-Derived Lipopolysaccharide (LPS) in LPS-Treated Human Neuronal-Glial (HNG) Cells in Primary Culture: Relevance to Alzheimer's ..." in: Frontiers in cellular neuroscience, Vol. 13, pp. 314, (2019) (PubMed).

Futai, Doty, Baek, Ryu, Sheng: "Specific trans-synaptic interaction with inhibitory interneuronal neurexin underlies differential ability of neuroligins to induce functional inhibitory synapses." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 8, pp. 3612-23, (2013) (PubMed).

Zeng, Zhang, Shi, Yamamoto, Lu, Wang: "Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models." in: PLoS ONE, Vol. 8, Issue 3, pp. e59685, (2013) (PubMed).

Tanaka, Fujii, Hirano: "Live-cell imaging of receptors around postsynaptic membranes." in: Nature protocols, Vol. 9, Issue 1, pp. 76-89, (2013) (PubMed).

Noelker, Schwake, Balzer-Geldsetzer, Bacher, Popp, Schlegel, Eggert, Oertel, Klockgether, Dodel: "Differentially expressed gene profile in the 6-hydroxy-dopamine-induced cell culture model of Parkinson's disease." in: Neuroscience letters, Vol. 507, Issue 1, pp. 10-5, (2012) (PubMed).

Yamagata, Sanes: "Transgenic strategy for identifying synaptic connections in mice by fluorescence complementation (GRASP)." in: Frontiers in molecular neuroscience, Vol. 5, pp. 18, (2012) (PubMed).

Bot, Schweizer, Ben Halima, Fraering: "Processing of the synaptic cell adhesion molecule neurexin-3beta by Alzheimer disease alpha- and gamma-secretases." in: The Journal of biological chemistry, Vol. 286, Issue 4, pp. 2762-73, (2011) (PubMed).

Lim, Kwon, Lee, Moon, Jeong, Park, Kim, Park, Lee, Ryu, Yu, Chung, Kim, Myung, Lee: "Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn." in: The EMBO journal, Vol. 28, Issue 22, pp. 3564-78, (2009) (PubMed).

Samuels, Hsueh, Shu, Liang, Tseng, Hong, Su, Volker, Neve, Yue, Tsai: "Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK." in: Neuron, Vol. 56, Issue 5, pp. 823-37, (2007) (PubMed).

Feng, Schroer, Yan, Song, Yang, Bockholt, Cook, Skinner, Schwartz, Sommer: "High frequency of neurexin 1beta signal peptide structural variants in patients with autism." in: Neuroscience letters, Vol. 409, Issue 1, pp. 10-3, (2006) (PubMed).

Synonyms and alternative names related to Neurexin 1

neurexin 1 (NRXN1), Neurexin 1 (Nrx-1), neurexin 1 (Nrxn1), neurexin 1 (Nrx-1), neurexin 1 (nrxn1), neurexin I (Nrxn1), neurexin 1b (nrxn1b), neurexin 1a (nrxn1a), 1700062G21Rik, 9330127H16Rik, A230068P09Rik, CG7050, CT21808, Dmel\\CG7050, dnrx, dnrx-1, GB13455, GB18754, Hs.22998, mKIAA0578, Nrx, nrx, Nrx-1, Nrx1, NRXN1, Nrxn1b, PTHSL2, SCZD17

Protein level used designations for Neurexin 1

  • neurexin I
  • neurexin-1-beta
  • CG7050-PA
  • CG7050-PB
  • CG7050-PC
  • CG7050-PD
  • CG7050-PE
  • CG7050-PF
  • CG7050-PG
  • CG7050-PH
  • Neurexin-1
  • Neurexin-like
  • Nrx-1-PA
  • Nrx-1-PB
  • Nrx-1-PC
  • Nrx-1-PD
  • Nrx-1-PE
  • Nrx-1-PF
  • Nrx-1-PG
  • Nrx-1-PH
  • drosophila neurexin
  • neurexin
  • neurexin 1
  • neurexin I-alpha
  • neurexin I-beta
  • neurexin-1-alpha
  • non-processed neurexin I-alpha
  • neurexin-1
  • neurexin I alpha
  • neurexin 1 alpha
  • neurexin 1 beta
  • neurexin-1-beta isoform alpha1
  • neurexin-1-beta isoform alpha2
  • neurexin I-like
  • neurexin-1-alpha-like
  • alpha-latrotoxin receptor (calcium-dependent)
  • neurexin Ib-alpha
  • neurexin Ib-beta
  • neurexin-1b-alpha
  • nrxn1ba
  • nrxn1bb
  • neurexin Ia-alpha
  • neurexin Ia-beta
  • neurexin-1a-alpha
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