Nephrin Products
(Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
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This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009].
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Featured Nephrin Categories
Nephrin Antibodies
High quality antibodies with extensive validation data.
Nephrin ELISA Kits
Reliable ELISA kits for a wide range of species.
Nephrin Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Nephrin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7432916
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7442111
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse, Rat
Application
FACS
Validations
- (2)
- (3)
Cat. No.
ABIN2177857
Quantity
100 μL
Datasheet
Datasheet
Recommended Nephrin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN6574241
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958053
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6958054
Quantity
96 tests
Datasheet
Datasheet
Recommended Nephrin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124129
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312871
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418107
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Nephrin products
: "miR-188-3p abolishes germacrone-mediated podocyte protection in a mouse model of diabetic nephropathy in type I diabetes through triggering mitochondrial injury." in: Bioengineered, (2021) (PubMed).: "Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria." in: Kidney international, Vol. 95, Issue 4, pp. 830-845, (2020) (PubMed).
: "Multiplex Bead Array Assay of a Panel of Circulating Cytokines and Growth Factors in Patients with Albuminuric and Non-AlbuminuricDiabetic Kidney Disease." in: Journal of clinical medicine, Vol. 9, Issue 9, (2020) (PubMed).
: "Astragaloside IV inhibits glucose-induced epithelial-mesenchymal transition of podocytes through autophagy enhancement via the SIRT-NF-κB p65 axis." in: Scientific reports, Vol. 9, Issue 1, pp. 323, (2019) (PubMed).
: "Renal protection by atorvastatin in a murine model of sickle cell nephropathy." in: British journal of haematology, Vol. 181, Issue 1, pp. 111-121, (2019) (PubMed).
: "Combination therapy of exendin-4 and allogenic adipose-derived mesenchymal stem cell preserved renal function in a chronic kidney disease and sepsis syndrome setting in rats." in: Oncotarget, Vol. 8, Issue 59, pp. 100002-100020, (2018) (PubMed).
: "Alteration of Connexin43 expression in a rat model of obesity-related glomerulopathy." in: Experimental and molecular pathology, Vol. 104, Issue 1, pp. 12-18, (2018) (PubMed).
: "Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation." in: JCI insight, Vol. 3, Issue 12, (2018) (PubMed).
: "The Ameliorative Effect of Pectin-Insulin Patch On Renal Injury in Streptozotocin-Induced Diabetic Rats." in: Kidney & blood pressure research, Vol. 42, Issue 3, pp. 530-540, (2018) (PubMed).
: "Podocyturia parallels proximal tubule dysfunction in type 2 diabetes mellitus patients independently of albuminuria and renal function decline: A cross-sectional study." in: Journal of diabetes and its complications, Vol. 31, Issue 9, pp. 1444-1450, (2018) (PubMed).
Synonyms and alternative names related to Nephrin
NPHS1, nephrin (NPHS1), nephrosis 1, congenital, Finnish type (nephrin) (nphs1), NPHS1 nephrin S homeolog (nphs1.S), nephrin (LOC5579127), NPHS1 nephrin (Nphs1), NPHS1, nephrin (Nphs1), nephrosis 1, nephrin (Nphs1), CNF, nephrin, NephrinB, NPHN, NPHS1, nphs1, nphs1lProtein level used designations for Nephrin
- nephrosis 1, congenital, Finnish type (nephrin)
- nephrin
- renal glomerulus-specific cell adhesion receptor
- nephrosis 1 homolog, nephrin
- nephrin 1
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