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NEK6 Products

(NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))

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The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Featured NEK6 Categories

NEK6 Antibodies

High quality antibodies with extensive validation data.

NEK6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NEK6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p), IP
Validations
  • (8)
Cat. No. ABIN1499686
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN657847
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1049089
Quantity 50 μg
Datasheet Datasheet

Recommended NEK6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
Cat. No. ABIN1312366
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312368
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509042
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NEK6 products

Takeno, Takemasa, Doki, Yamasaki, Miyata, Takiguchi, Fujiwara, Matsubara, Monden: "Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis." in: British journal of cancer, Vol. 99, Issue 8, pp. 1307-15, (2008) (PubMed).

Belham, Roig, Caldwell, Aoyama, Kemp, Comb, Avruch: "A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases." in: The Journal of biological chemistry, Vol. 278, Issue 37, pp. 34897-909, (2003) (PubMed).

Lizcano, Deak, Morrice, Kieloch, Hastie, Dong, Schutkowski, Reimer, Alessi et al.: "Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and ..." in: The Journal of biological chemistry, Vol. 277, Issue 31, pp. 27839-49, (2002) (PubMed).

Hashimoto, Akita, Hibino, Kohri, Nakanishi: "Identification and characterization of Nek6 protein kinase, a potential human homolog of NIMA histone H3 kinase." in: Biochemical and biophysical research communications, Vol. 293, Issue 2, pp. 753-8, (2002) (PubMed).

Synonyms and alternative names related to NEK6

NIMA (never in mitosis gene a)-related expressed kinase 6 (Nek6), NIMA-related kinase 6 (nek6), NIMA related kinase 6 (NEK6), Serine/Threonine kinase catalytic domain protein (NEK5), NIMA-related kinase 6 S homeolog (nek6.S), NIMA-related kinase 6 (Nek6), 1300007C09Rik, ATNEK5, MOE17.17, NIMA-RELATED KINASE5, NIMA-related kinase 5, si:ch211-167p9.4, SID6-1512

Protein level used designations for NEK6

  • NIMA-related expressed kinase 6
  • never in mitosis A-related kinase 6
  • nimA-related protein kinase 6
  • serine/threonine-protein kinase Nek6
  • putative serine-threonine protein kinase
  • NIMA (never in mitosis gene a)-related kinase 6
  • protein kinase SID6-1512
  • NIMA (never in mitosis gene a)-related expressed kinase 6
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