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NEK3 Products

(NIMA related kinase 3 (NEK3))

Categories

This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].

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Featured NEK3 Categories

NEK3 Antibodies

High quality antibodies with extensive validation data.

NEK3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NEK3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN652427
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN561960
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7169101
Quantity 100 μL
Datasheet Datasheet

Recommended NEK3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951293
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210031
Quantity 96 tests
Datasheet Datasheet

Recommended NEK3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312360
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312358
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7320002
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our NEK3 products

Harrington, Clevenger: "Identification of NEK3 Kinase Threonine 165 as a Novel Regulatory Phosphorylation Site That Modulates Focal Adhesion Remodeling Necessary for Breast Cancer Cell Migration." in: The Journal of biological chemistry, Vol. 291, Issue 41, pp. 21388-21406, (2016) (PubMed).

McHale, Tomaszewski, Puthiyaveettil, Livolsi, Clevenger: "Altered expression of prolactin receptor-associated signaling proteins in human breast carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 5, pp. 565-71, (2008) (PubMed).

Kimura, Okano: "Molecular cloning and characterization of the human NIMA-related protein kinase 3 gene (NEK3)." in: Cytogenetics and cell genetics, Vol. 95, Issue 3-4, pp. 177-82, (2002) (PubMed).

Synonyms and alternative names related to NEK3

NIMA related kinase 3 (NEK3), NIMA (never in mitosis gene a)-related expressed kinase 3 (Nek3), NIMA-related kinase 3 S homeolog (nek3.S), NIMA-related kinase 3 (Nek3), NIMA-related kinase 3 (NEK3), ATNEK3, HSPK36, NIMA-RELATED KINASE3, NIMA-related kinase 3, T8M17.60, T8M17_60

Protein level used designations for NEK3

  • NIMA-related expressed kinase 3
  • never in mitosis A-related kinase 3
  • nimA-related protein kinase 3
  • serine/threonine-protein kinase Nek3
  • NIMA (never in mitosis gene a)-related kinase 3
  • HSPK 36
  • glycogen synthase A kinase
  • hydroxyalkyl-protein kinase
  • phosphorylase B kinase kinase
  • NIMA (never in mitosis gene a)-related expressed kinase 3
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