NEK3 Products
(NIMA related kinase 3 (NEK3))
Categories
This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].
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Featured NEK3 Categories
NEK3 Antibodies
High quality antibodies with extensive validation data.
NEK3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NEK3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (3)
Cat. No.
ABIN652427
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN561960
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7169101
Quantity
100 μL
Datasheet
Datasheet
Recommended NEK3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951293
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6210031
Quantity
96 tests
Datasheet
Datasheet
Recommended NEK3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312360
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312358
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7320002
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our NEK3 products
: "Identification of NEK3 Kinase Threonine 165 as a Novel Regulatory Phosphorylation Site That Modulates Focal Adhesion Remodeling Necessary for Breast Cancer Cell Migration." in: The Journal of biological chemistry, Vol. 291, Issue 41, pp. 21388-21406, (2016) (PubMed).: "Altered expression of prolactin receptor-associated signaling proteins in human breast carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 5, pp. 565-71, (2008) (PubMed).
: "Molecular cloning and characterization of the human NIMA-related protein kinase 3 gene (NEK3)." in: Cytogenetics and cell genetics, Vol. 95, Issue 3-4, pp. 177-82, (2002) (PubMed).
Synonyms and alternative names related to NEK3
NIMA related kinase 3 (NEK3), NIMA (never in mitosis gene a)-related expressed kinase 3 (Nek3), NIMA-related kinase 3 S homeolog (nek3.S), NIMA-related kinase 3 (Nek3), NIMA-related kinase 3 (NEK3), ATNEK3, HSPK36, NIMA-RELATED KINASE3, NIMA-related kinase 3, T8M17.60, T8M17_60Protein level used designations for NEK3
- NIMA-related expressed kinase 3
- never in mitosis A-related kinase 3
- nimA-related protein kinase 3
- serine/threonine-protein kinase Nek3
- NIMA (never in mitosis gene a)-related kinase 3
- HSPK 36
- glycogen synthase A kinase
- hydroxyalkyl-protein kinase
- phosphorylase B kinase kinase
- NIMA (never in mitosis gene a)-related expressed kinase 3
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