NEK2 Products
(NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2))
Categories
This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011].
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Featured NEK2 Categories
NEK2 Antibodies
High quality antibodies with extensive validation data.
NEK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
NEK2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NEK2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7439456
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC (p)
Validations
- (5)
Cat. No.
ABIN561955
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN561956
Quantity
100 μg
Datasheet
Datasheet
Recommended NEK2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5525181
Quantity
96 tests
Datasheet
Datasheet
Recommended NEK2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312356
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509038
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7416697
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NEK2 products
: "MicroRNA-128 promotes apoptosis in lung cancer by directly targeting NIMA-related kinase 2." in: Thoracic cancer, Vol. 8, Issue 4, pp. 304-311, (2018) (PubMed).: "NEK2 regulates stem-like properties and predicts poor prognosis in hepatocellular carcinoma." in: Oncology reports, Vol. 36, Issue 2, pp. 853-62, (2017) (PubMed).
: "Overexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer." in: BMC urology, Vol. 15, pp. 90, (2015) (PubMed).
: "Examining Nek2 as a better proliferation marker in non-small cell lung cancer prognosis." in: Tumour biology, Vol. 35, Issue 7, pp. 7155-62, (2014) (PubMed).
: "Aberrant expression of NEK2 and its clinical significance in non-small cell lung cancer." in: Oncology letters, Vol. 8, Issue 4, pp. 1470-1476, (2014) (PubMed).
: "The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival." in: Nucleic acids research, Vol. 42, Issue 5, pp. 3218-27, (2014) (PubMed).
: "Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity." in: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 28-40, (2014) (PubMed).
: "Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation." in: The Journal of cell biology, Vol. 188, Issue 1, pp. 83-100, (2010) (PubMed).
: "Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas." in: The Journal of pathology, Vol. 217, Issue 3, pp. 431-41, (2009) (PubMed).
: "Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26431-40, (2007) (PubMed).
Synonyms and alternative names related to NEK2
NIMA related kinase 2 (NEK2), NIMA (never in mitosis gene a)-related expressed kinase 2 (Nek2), NIMA-related kinase 2 (Nek2), NIMA-related kinase 2 (NEK2), AA617254, ATNEK2, C77054, HsPK21, NEK2A, NIMA-RELATED KINASE2, NIMA-related kinase 2, NLK1, T9J14.24, T9J14_24Protein level used designations for NEK2
- NIMA (never in mitosis gene a)-related kinase 2
- NIMA - related expressed kinase 2
- NIMA-related expressed kinase 2
- NIMA-related kinase 2
- Nek2 kinase
- never in mitosis A-related kinase 2
- nimA-related protein kinase 2
- serine/threonine-protein kinase Nek2
- serine/threonine protein kinase Nek2
- nimA-like protein kinase 1
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