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NEFM Products

(Neurofilament Triplet M Protein (NEFM))
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].

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Featured NEFM Categories

NEFM Antibodies

High quality antibodies with extensive validation data.

NEFM ELISA Kits

Reliable ELISA kits for a wide range of species.

NEFM Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NEFM Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (6)
Cat. No. ABIN5542346
Quantity 100 μL
Datasheet Datasheet
Reactivity Mammalian
Application WB, ICC, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN94435
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN2683002
Quantity 100 μL
Datasheet Datasheet

Recommended NEFM ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6962098
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968862
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958100
Quantity 96 tests
Datasheet Datasheet

Recommended NEFM Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505037
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424176
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393808
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our NEFM products

Glass, Kelm-Nelson, Szot, Lake, Connor, Ciucci: "Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." in: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).

Martineau, Di Polo, Vande Velde, Robitaille: "Dynamic neuromuscular remodeling precedes motor-unit loss in a mouse model of ALS." in: eLife, Vol. 7, (2019) (PubMed).

Kim, Kim, Park, Jeon, Lee, Yoo, Lee, Moon, Yu, Kim: "Tanycytic TSPO inhibition induces lipophagy to regulate lipid metabolism and improve energy balance." in: Autophagy, pp. 1-21, (2019) (PubMed).

Jacobsen, Lett, Barden, Simpson, Buttigieg: "Activation of the Large-Conductance, Voltage, and Ca2+- Activated K+ (BK) Channel in Acute Spinal Cord Injury in the Wistar Rat Is Neuroprotective." in: Frontiers in neurology, Vol. 9, pp. 1107, (2018) (PubMed).

Sikora, Dworski, Jones, Kamani, Micsenyi, Sawada, Le Faouder, Bertrand-Michel, Dupuy, Dunn, Xuan, Casas, Fabrias, Hampson, Levade, Drake, Medin, Walkley: "Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities." in: The American journal of pathology, Vol. 187, Issue 4, pp. 864-883, (2017) (PubMed).

Yuan, Sun, Yu, An: "Human microvascular endothelial cell promotes the development of dorsal root ganglion neurons via BDNF pathway in a co-culture system." in: Bioscience, biotechnology, and biochemistry, Vol. 81, Issue 7, pp. 1335-1342, (2017) (PubMed).

Getz, Xu, Visser, Persson, Syed: "Tumor suppressor menin is required for subunit-specific nAChR α5 transcription and nAChR-dependent presynaptic facilitation in cultured mouse hippocampal neurons." in: Scientific reports, Vol. 7, Issue 1, pp. 1768, (2017) (PubMed).

Chu, Cummins, Sparling, Tsutsui, Brideau, Nilsson, Joseph, Stys: "Axonal and myelinic pathology in 5xFAD Alzheimer's mouse spinal cord." in: PLoS ONE, Vol. 12, Issue 11, pp. e0188218, (2017) (PubMed).

Sikora, Leddy, Gulinello, Walkley: "X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities." in: Disease models & mechanisms, Vol. 9, Issue 1, pp. 13-23, (2016) (PubMed).

Xu, Armstrong, Urrego, Qazzaz, Pehar, Armstrong, Shutt, Syed: "The mitochondrial division inhibitor Mdivi-1 rescues mammalian neurons from anesthetic-induced cytotoxicity." in: Molecular brain, Vol. 9, pp. 35, (2016) (PubMed).

Synonyms and alternative names related to NEFM

neurofilament medium (NEFM), neurofilament medium (Nefm), neurofilament triplet M protein (TVAG_582010), neurofilament triplet M protein (TVAG_379630), neurofilament, medium polypeptide (Nefm), neurofilament medium polypeptide (NEFM), neurofilament, medium polypeptide (NEFM), neurofilament medium L homeolog (nefm.L), neurofilament, medium polypeptide a (nefma), neurofilament medium S homeolog (nefm.S), nef-m, NEF3, Nef3, nef3, nefm, nefm-a, nefm-b, NF-M, nf-m, NF160, NF165, NFM, Nfm, zgc:112359

Protein level used designations for NEFM

  • 160 kDa neurofilament protein
  • neurofilament 3
  • neurofilament medium polypeptide
  • neurofilament triplet M protein
  • neurofilament, medium polypeptide 150kDa
  • neurofilament-3 (150 kD medium)
  • NF-M
  • Neurofilament protein, middle polypeptide
  • neurofilament 3, medium
  • neurofilament protein M
  • neurofilament-M
  • major neuronal intermediate filament subunit
  • neurofilament M subunit
  • NF-M c-terminus
  • NF-M protein
  • neurofilament 3 (150kDa medium)
  • middle molecular weight neurofilament protein NF-M(1)
  • neurofilament, medium polypeptide
  • middle molecular weight neurofilament protein NF-M(2)
  • neurofilament medium S homeolog
  • neurofilament, medium polypeptide S homeolog
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