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NEFH Products

(Neurofilament, Heavy Polypeptide (NEFH))
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008].

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Featured NEFH Categories

NEFH Antibodies

High quality antibodies with extensive validation data.

NEFH ELISA Kits

Reliable ELISA kits for a wide range of species.

NEFH Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NEFH Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (6)
Cat. No. ABIN7193619
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, FACS, ELISA
Validations
  • (7)
Cat. No. ABIN7193620
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7264479
Quantity 200 μL
Datasheet Datasheet

Recommended NEFH ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971292
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962681
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958102
Quantity 96 tests
Datasheet Datasheet

Recommended NEFH Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312336
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7385334
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406797
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our NEFH products

Malara, Lutz, Incearap, Bauer, Cursano, Volbracht, Lerner, Pandey, Delling, Ioannidis, Arévalo, von Bernhardi, Schön, Bockmann, Dimou, Boeckers: "SHANK3 deficiency leads to myelin defects in the central and peripheral nervous system." in: Cellular and molecular life sciences : CMLS, Vol. 79, Issue 7, pp. 371, (2022) (PubMed).

Picchiarelli, Demestre, Zuko, Been, Higelin, Dieterlé, Goy, Mallik, Sellier, Scekic-Zahirovic, Zhang, Rosenbohm, Sijlmans, Aly, Mersmann, Sanjuan-Ruiz, Hübers, Messaddeq, Wagner, van Bakel et al.: "FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis. ..." in: Nature neuroscience, Vol. 22, Issue 11, pp. 1793-1805, (2020) (PubMed).

Lackington, Kočí, Alekseeva, Hibbitts, Kneafsey, Chen, OBrien et al.: "Controlling the dose-dependent, synergistic and temporal effects of NGF and GDNF by encapsulation in PLGA microparticles for use in nerve guidance conduits for the repair of large peripheral nerve ..." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 304, pp. 51-64, (2019) (PubMed).

Hutter-Schmid, Humpel: "Primary mouse brain pericytes isolated from transgenic Alzheimer mice spontaneously differentiate into a CD11b+ microglial-like cell type in vitro." in: Experimental gerontology, Vol. 112, pp. 30-37, (2018) (PubMed).

Li, Zang, He, Chen, Yu, Pei, Hou, An, Yang, Zhang, Liu: "Expression of pannexin 1 and 2 in cortical lesions from intractable epilepsy patients with focal cortical dysplasia." in: Oncotarget, Vol. 8, Issue 4, pp. 6883-6895, (2018) (PubMed).

Liu, Lv, Zhu, Wu, Zhang, Xu, Zheng, Zhao: "Salidroside promotes peripheral nerve regeneration based on tissue engineering strategy using Schwann cells and PLGA: in vitro and in vivo." in: Scientific reports, Vol. 7, pp. 39869, (2018) (PubMed).

Xu, Hu, Jiang, Pan, Shen, Schachner: "Trimebutine, a small molecule mimetic agonist of adhesion molecule L1, contributes to functional recovery after spinal cord injury in mice." in: Disease models & mechanisms, Vol. 10, Issue 9, pp. 1117-1128, (2018) (PubMed).

Huang, Lin, Jiang, Chen, Mei, Zhu: "Effects of intra-arterial transplantation of adipose-derived stem cells on the expression of netrin-1 and its receptor DCC in the peri-infarct cortex after experimental stroke." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 223, (2018) (PubMed).

Zheng, Chen, Chen, Zhang, Chen, Lin, Lan, Yuan, Lai, Jiang, Pan, Liu: "Netrin-1 Promotes Synaptic Formation and Axonal Regeneration via JNK1/c-Jun Pathway after the Middle Cerebral Artery Occlusion." in: Frontiers in cellular neuroscience, Vol. 12, pp. 13, (2018) (PubMed).

Foidl, Humpel: "Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid." in: Frontiers in aging neuroscience, Vol. 10, pp. 113, (2018) (PubMed).

Synonyms and alternative names related to NEFH

neurofilament heavy polypeptide (MCYG_06231), neurofilament, heavy polypeptide (Nefh), neurofilament heavy (Nefh), neurofilament heavy (NEFH), neurofilament heavy polypeptide (NEFH), mKIAA0845, NEFH, NF-H, NF200, Nfh, NFH

Protein level used designations for NEFH

  • neurofilament heavy polypeptide
  • 200 kDa neurofilament protein
  • neurofilament 200kDa
  • neurofilament triplet H protein
  • NF-H
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament, heavy polypeptide
  • neurofilament, heavy polypeptide 200kDa-like
  • heavy neurofilament protein
  • intermediate filament protein
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