NEDD9 Products
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
Categories
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
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Featured NEDD9 Categories
NEDD9 Antibodies
High quality antibodies with extensive validation data.
NEDD9 ELISA Kits
Reliable ELISA kits for a wide range of species.
NEDD9 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NEDD9 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (9)
Cat. No.
ABIN3023331
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (4)
Cat. No.
ABIN6263585
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (3)
Cat. No.
ABIN561951
Quantity
50 μg
Datasheet
Datasheet
Recommended NEDD9 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968848
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1131949
Quantity
96 tests
Datasheet
Datasheet
Recommended NEDD9 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312332
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312334
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3090359
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NEDD9 products
: "Overexpression of NEDD9 promotes cell invasion and metastasis in hepatocellular carcinoma." in: Clinics and research in hepatology and gastroenterology, Vol. 41, Issue 6, pp. 677-686, (2018) (PubMed).: "Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability." in: Immunology and cell biology, Vol. 94, Issue 10, pp. 981-993, (2016) (PubMed).
: "NEDD9 overexpression correlates with poor prognosis in gastric cancer." in: Tumour biology, Vol. 35, Issue 7, pp. 6351-6, (2014) (PubMed).
: "The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway." in: Oncogene, Vol. 32, Issue 14, pp. 1811-20, (2013) (PubMed).
: "The overexpression of scaffolding protein NEDD9 promotes migration and invasion in cervical cancer via tyrosine phosphorylated FAK and SRC." in: PLoS ONE, Vol. 8, Issue 9, pp. e74594, (2013) (PubMed).
: "NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration." in: PLoS ONE, Vol. 7, Issue 4, pp. e35058, (2012) (PubMed).
: "Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation." in: The Journal of biological chemistry, Vol. 285, Issue 28, pp. 21526-36, (2010) (PubMed).
: "Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. ..." in: Human molecular genetics, Vol. 17, Issue 5, pp. 759-67, (2008) (PubMed).
: "Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene." in: Cell, Vol. 125, Issue 7, pp. 1269-81, (2006) (PubMed).
: "The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking." in: Immunity, Vol. 25, Issue 6, pp. 907-18, (2006) (PubMed).
Synonyms and alternative names related to NEDD9
neural precursor cell expressed, developmentally down-regulated 9 (NEDD9), neural precursor cell expressed, developmentally down-regulated 9 (Nedd9), neural precursor cell expressed, developmentally down-regulated gene 9 (Nedd9), CAS-L, Cas-L, CAS2, CASL, CasL, CASS2, E230025G09Rik, HEF1, NEDD9Protein level used designations for NEDD9
- neural precursor cell expressed, developmentally down-regulated 9
- enhancer of filamentation 1 homolog
- Cas scaffolding protein family member 2
- Crk-associated substrate related protein Cas-L
- Enhancer of filamentation 1 p55
- cas-like docking
- enhancer of filamentation 1
- neural precursor cell expressed developmentally down-regulated protein 9
- p130Cas-related protein
- renal carcinoma antigen NY-REN-12
- neural precursor cell expressed, developmentally down-regulated gene 9
- CRK-associated substrate-related protein
- Crk-associated substrate lymphocyte-specific protein
- NEDD-9
- mEF1
- p105
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