Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

NEDD4-2 Products

(E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))

Categories

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured NEDD4-2 Categories

NEDD4-2 Antibodies

High quality antibodies with extensive validation data.

NEDD4-2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NEDD4-2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IP
Validations
  • (4)
Cat. No. ABIN525093
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6144504
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7264127
Quantity 200 μL
Datasheet Datasheet

Recommended NEDD4-2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231540
Quantity 96 tests
Datasheet Datasheet

Recommended NEDD4-2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312322
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312326
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136435
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NEDD4-2 products

Raikwar, Thomas: "Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1157-65, (2008) (PubMed).

Synonyms and alternative names related to NEDD4-2

neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (NEDD4L), NEDD4L (LOC776799), neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog (nedd4l.S), neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (Nedd4l), neural precursor cell expressed, developmentally down-regulated gene 4-like (Nedd4l), 1300012C07Rik, hNEDD4-2, nedd4, NEDD4, NEDD4-2, nedd4-2, Nedd4-2, NEDD4.2, Nedd4b, RSP5

Protein level used designations for NEDD4-2

  • E3 ubiquitin-protein ligase NEDD4-like
  • E3 ubiquitin-protein ligase NEDD4-like protein
  • ubiquitin-protein ligase Rsp5
  • neural precursor cell expressed, developmentally down-regulated 4
  • NEDD4.2
  • neural precursor cell expressed, developmentally down-regulated gene 4b
You are here:
Support